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Editorial Comment|Articles in Press

Quantifying the eyeball test: grip strength at the nexus of frailty, cachexia and sarcopenia in heart failure

      I know it when I see it...” – This famous phrase, written by Supreme Court Justice Potter Stewart in his concurrence to the majority decision in Jacobellis vs. Ohio in 1964, has a well-known parallel in clinical medicine: the “eyeball” test. Perhaps nowhere in cardiovascular medicine is the eyeball test more widely applied than in the assessment of frailty, a clinical entity marked by changes in physiologic and cognitive function that leaves an individual more susceptible to adverse outcomes in response to stress. The eyeball test is frequently central in clinical decision-making. However, quantitative analyses of the eyeball test have shown that clinicians: (1) do not accurately assess frailty and its associated risks; (2) are better at correctly identifying non-frail rather than frail patients; and (3) exhibit high inter-observer variability when attempting to gauge frailty.
      • Jain R
      • Duval S
      • Adabag S.
      How accurate is the eyeball test?: a comparison of physician's subjective assessment versus statistical methods in estimating mortality risk after cardiac surgery.
      • Hii TB
      • Lainchbury JG
      • Bridgman PG.
      Frailty in acute cardiology: comparison of a quick clinical assessment against a validated frailty assessment tool.
      • Ahmed A
      • Sorajja P
      • Pai A
      • Plimpton N
      • Bae R
      • Pedersen WA
      • et al.
      Prospective Evaluation of the Eyeball Test for Assessing Frailty in Patients With Valvular Heart Disease.
      • McDonagh J
      • Prichard R
      • Ferguson C
      • Phillips JL
      • Davidson PM
      • Macdonald PS
      • et al.
      Clinician Estimates of Frailty Compared to Formal Frailty Assessment in Adults With Heart Failure: A Cross-Sectional Analysis.
      Hence, the eyeball test is neither accurate nor precise.
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