Advertisement
Journal of Cardiac Failure Home
Advanced searchSave search
JCF Ignite!|Articles in Press

Voluntary Reporting of Guideline-Directed Medical Therapy Use Rates in the Public Domain: A Challenge to the Heart Failure Community

Published:February 20, 2023DOI:https://doi.org/10.1016/j.cardfail.2023.02.002
Voluntary Reporting of Guideline-Directed Medical Therapy Use Rates in the Public Domain: A Challenge to the Heart Failure Community
Previous ArticleHFSA Expert Consensus Statement on the Medical Management of Patients on Durable Mechanical Circulatory Support
Next ArticleRationale, Design and Baseline Characteristics of the PARAGLIDE-HF Trial: Sacubitril/Valsartan vs Valsartan in HFmrEF and HFpEF With a Worsening Heart Failure Event
      Achieving target or maximally tolerated doses of Guideline Directed Medical Therapy (GDMT) is associated with decreased morbidity and mortality rates in patients with heart failure and reduced ejection fraction (HFrEF).
      • Greene SJ
      • Butler J
      • Hellkamp AS
      • Spertus JA
      • Vaduganathan M
      • Devore AD
      • et al.
      Comparative effectiveness of dosing of medical therapy for heart failure: from the CHAMP-HF registry.
      J Card Fail. 2022; 28: 370-384
      However, in a contemporary cohort of outpatients with HFrEF, the percentage of patients achieving target dosages of GDMT was woefully low, with < 1% of patients achieving target dosages of 3 foundational components of GDMT: (ACE [angiotensin converting enzyme inhibitor], ARB [angiotensin receptor blocker], or ARNI [angiotensin receptor/neprilysin inhibitor]); beta-blocker; and MRA [mineralocorticoid receptor antagonist] at 1-year follow-up.
      • Greene SJ
      • Fonarow GC
      • DeVore AD
      • Sharma PP
      • Vaduganathan M
      • Albert NM
      • et al.
      Titration of medical therapy for heart failure with reduced ejection fraction.
      J Am Coll Cardiol. 2019; 73: 2365-2383

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Cardiac Failure
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Greene SJ
        • Butler J
        • Hellkamp AS
        • Spertus JA
        • Vaduganathan M
        • Devore AD
        • et al.
        Comparative effectiveness of dosing of medical therapy for heart failure: from the CHAMP-HF registry.
        J Card Fail. 2022; 28: 370-384
        View in Article
        • Greene SJ
        • Fonarow GC
        • DeVore AD
        • Sharma PP
        • Vaduganathan M
        • Albert NM
        • et al.
        Titration of medical therapy for heart failure with reduced ejection fraction.
        J Am Coll Cardiol. 2019; 73: 2365-2383
        View in Article
        • Drazner MH
        Implementation of the 2022 ACC/AHA/HFSA Heart Failure Guideline: a call to action.
        J Card Fail. 2022; 28: 878-880
        View in Article
        • Heidenreich PA
        • Hernandez AF
        • Yancy CW
        • Liang L
        • Peterson ED
        • Fonarow GC
        Get With The Guidelines program participation, process of care, and outcome for Medicare patients hospitalized with heart failure.
        Circ Cardiovasc Qual Outcomes. 2012; 5: 37-43
        View in Article
        • Heidenreich PA
        • Fonarow GC
        • Breathett K
        • Jurgens CY
        • Pisani BA
        • Pozehl BJ
        • et al.
        2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.
        J Am Coll Cardiol. 2020; 76: 2527-2564
        View in Article

      Article info

      Publication history

      Published online: February 20, 2023
      Accepted: February 10, 2023
      Received in revised form: February 10, 2023
      Received: February 6, 2023

      Publication stage

      In Press Journal Pre-Proof

      Identification

      DOI: https://doi.org/10.1016/j.cardfail.2023.02.002

      Copyright

      © 2023 Elsevier Inc. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX