Highlights
- •Modified HIIT is safe in patients with LVADs.
- •Short bouts of HIIT are feasible and improve VO2 peak and functional parameters.
ABSTRACT
Background
High-intensity interval training (HIIT) of 4 minutes at 80%–90% of peak oxygen consumption
(VO2peak) has been shown to be feasible in patients with left ventricular assist devices (LVADs).
The effect of shorter bouts of HIIT, which reduce the anaerobic burden, has not been
investigated compared to moderate continuous training (MCT).
Methods and Results
We conducted a prospective, monocentric study (NCT05121077) randomizing patients with
LVADs into 20 minutes of MCT (n = 10) or short bouts (≤ 90 seconds) of HIIT (n = 10)
following cardiopulmonary exercise testing at 50%–60% and 80%–90% of VO2peak. Each of the 18 supervised sessions (3×/week, t0–t1) included 10 minutes of strengthening training. The primary outcome was the increase
of VO2peak in the 2 groups between t0 and t1. Secondary outcomes were changes in the 12-item Kansas City Cardiomyopathy Questionnaire,
the 6-minute walk distance and the percentage of VO2peak at the first ventilatory threshold. VO2peak significantly increased with HIIT (13.0 ± 4.6mL/kg/min vs 14.6 ± 4.3mL/kg/min; P = 0.037), but not with MCT (11.8 ± 3.3mL/kg/min vs 13.1 ± 3.3mL/kg/min; P = 0.322), without between-group differences (P = 0.853). Secondary outcomes improved from t0–t1 in MCT and HIIT, without differences between the groups.
Conclusions
Short bouts of HIIT are feasible, and they improved VO2peak and functional parameters in patients in this pilot prospective study.
Key Words
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References
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Article info
Publication history
Published online: February 07, 2023
Accepted:
January 26,
2023
Received in revised form:
January 19,
2023
Received:
December 19,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
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#HIIT in LVAD: High-intensity interval training is both safe and beneficial in patients with LVADs.
Identification
Copyright
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