- •The HeartMate 3 left ventricular assist device is now the only centrifugal pump intended for durable support being actively manufactured and implanted for adults in the United States, although patients with previously implanted HeartMate II devices continue to be actively cared for across the country.
- •The changes in hemodynamics that accompany common clinical scenarios experienced by left ventricular assist device patients will cause specific changes to the left ventricular assist device pump parameters, such as pump power, pulsatility index, and flow.
- •A full understanding of these variables, as well as the underlying physiologic principles governing their derivation, is necessary to provide optimal care for this growing patient population.
- •This review describes pump parameter physiology, as well as the application of pump parameter interpretation to common clinical scenarios.
The HeartMate 3 left ventricular assist device (LVAD) is now the only centrifugal pump intended for durable support being actively manufactured and implanted for adults in the United States. The changes in preload and afterload that accompany common clinical scenarios experienced by patients with an LVAD will cause specific changes to the LVAD pump parameters, namely, the pump power, pulsatility index, and flow. Appropriate care of this unique, and growing, population requires a full understanding of these variables as well as the underlying physiologic principles governing their derivation. The aim of this review is to focus on the updated functionality of the HeartMate 3, specifically in comparison to the HeartMate II, as well as the application of pump parameter interpretation to common clinical scenarios.
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Published online: December 31, 2021
Accepted: November 1, 2021
Received in revised form: October 10, 2021
Received: August 24, 2021
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