Abstract
Background
The bioreactance technique is a relatively new, totally noninvasive technique that
is used to measure cardiac output (CO) and is easy to use. The Non-Invasive Cardiac
Output Monitor (NICOM) is 1 such system. Although approved by the Food and Drug Administration
for measurement of stroke volume, there is a paucity of literature validating this
technology in decompensated heart failure and cardiogenic shock.
Methods and Results
Fifty patients admitted to our cardiac intensive care unit for cardiogenic shock and
Swan-Ganz catheter-guided therapy were prospectively enrolled in the study after informed
consent. Simultaneous measurements of CO were obtained using NICOM, indirect Fick
and bolus thermodilution. The intraclass correlation coefficient (ICC) was used to
assess the precision of NICOM for CO using the 3 repeated measurements of CO over
the pooled data. The agreement of the NICOM device in the defined clinical population,
compared to indirect Fick and thermodilution, was evaluated by comparing the Pearson
correlation coefficient, the Bland-Altman plot and the Lin concordance correlation
coefficient. The ICC for cardiac output measured by NICOM showed excellent repeatability
(ICC = 0.93, 95% CI = 0.92–0.94, n = 262) in the pooled data. The Pearson correlation
coefficient for cardiac output measured by NICOM was poor when compared to indirect
Fick (n = 263, r = 0.132, P = 0.033) and TD (n = 258, r = 0.275, P < 0.001).
Conclusions
NICOM technology is not a reliable method of measuring CO in patients with decompensated
heart failure and cardiogenic shock.
Key Words
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Article Info
Publication History
Published online: November 18, 2019
Accepted:
November 13,
2019
Received in revised form:
October 13,
2019
Received:
July 12,
2019
Footnotes
Funding: Our study was funded through the Heart Failure Research grant # 40541 at The University of Kansas Medical Center .
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.

