Aim: The purpose of this study is to evaluate the efficacy of TLV for the initially hospitalized
patients with ADHF. Methods: From 2011 to 2013, consecutive 124 patients initially hospitalized with a diagnosis
of ADHF (clinical scenario 2/5) at Nagoya Heart Center. They were treated with or
without TLV (TLV (−); n = 81, TLV (+); n = 43). We retrospectively analyzed the clinical
outcome of these patients. Results: The results are shown in the Table 1 and Fig. 1. 39.5% of cases were re-hospitalized.
In the re-hospitalized cases, the incidence of WRF was significantly higher. Conclusion: the treatment with tolvaptan could shortened the duration of bed-rest and prevent
WRF and re-hospitalization. The results of this study suggest tolvaptan initiated
for acute treatment of patients initially hospitalized with ADHF had effect outcome
in daily clinical practice.
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