Abstract| Volume 23, ISSUE 10, SUPPLEMENT , S77-S78, October 2017

Practical and Prognostic Impact of Urine Specific Gravity in Acute Heart Failure

      Background: The clinical significance of urine specific gravity (USG) in acute heart failure (AHF) is unknown. Methods and Results: USG was measured from spot urine on admission in 72 consecutive AHDF patients, excluding those with glycosuria and proteinurea. The patients were divided into 2 groups based on the median values (1.011) of USG. There was no significant difference, except stroke volume (34 ± 11 vs 55 ± 28 mL, P < .001) and initial dobutamine use (31 vs 12%, P < .01). Kaplan-Meier curves demonstrated that low USG group was associated with a significantly lower cardiac-event-free rate (P = .02, Fig. 1) and was an independent predictor for the cardiac events (adjusted hazard ratio = 0.91; 95% confidence interval, 0.82–0.99; P < .01). Conclusion: USG on admission indicates hypoperfusion and worse prognosis in AHF.
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