Background: Sleep apnea syndrome (SAS) is associated with a poor prognosis in patients with heart
failure (HF). However, the prevalence of SAS in elderly patients >80 years with HF
remains unknown. Methods: Seventy-six patients >80 years who underwent screening for SAS by oxygen saturation
monitoring with pulse oximetry were recruited into this study (84.4 ± 4.1 years, 80–98
years). Polysomonography (PSG) was performed in the patients with SAS defined as a
3% oxygen desaturation index (ODI > 3%) of >20. We checked the BMI, echocardiogram,
and serum BNP level. The patients were divided into two groups according to the presence
of HF (HF group n = 48, 84.8 ± 4.6 years, 19 males and non-HF group n = 28, 83.8 ± 2.8
years, 14 males). The HF criteria were as follows: a history of an admission for HF,
BNP level > 100 pg/mL, and LVEF < 40%. Results: The LVEF in the HF group was lower than in the non-HF group (56.4 ± 15.9 vs 67.9 ± 7.2%,
P < .01). The BNP level in the HF group was higher than in the non-HF group (337.4 ± 48.7
vs 61.3 ± 15.6 pg/mL, P < .001). The BMI did not differ. The prevalence of SAS in the HF group was higher
than in the non-HF group (39 [81%] vs 8 [29%], P < .001). 17 (74%) of the 23 patients who underwent PSG in the HF group had central
SAS. Conclusions: This study demonstrated a high prevalence of SAS, especially central SAS, in elderly
HF patients.
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