Background: It has been reported that heart failure is frequently concomitant with sleep disordered
breathing (SDB) and hypoxia is a worsening factor of heart failure. The purpose of
this study it to evaluate prognostic impact of SDB in patients with acute decompensate
heart failure (ADHF). Methods: Consecutive 213 patients (76.3 ± 12.0 years, males, 49.8%) with ADHF emergently admitted
to our hospital from September 2015 to March 2017 were enrolled and performed overnight
oximetry with PULSOX-Me300 before discharge. We examined and calculated 3% oxygen
desaturated index (ODI), and mean SpO2, and defined SDB positive as 3%ODI>15, and
low SpO2 as mean SpO2 <95, and investigated prognosis as re-admission of heart failure.
Results: 3%ODI was 16.4 ± 12.6 and SDB positive were 96 patients. Median of mean SpO2 was
95.1% (93.8–96.3) and low SpO2 were 106 patients. 44 patients were re-admitted for
heart failure, and Kaplan-Meier analysis revealed that low SpO2 group had worse prognosis
than normal SpO2 group, on the other hand, SDB positive was not significant (log-rank
P = .011 and P = .738, respectively). Conclusions: Low mean SpO2 was associated with increasing risk for re-admission in patients with
ADHF.
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