Abstract| Volume 23, ISSUE 10, SUPPLEMENT , S53, October 2017

Prognostic Impact of Sleep Disordered Breathing in Patients with Acute Decompensate Heart Failure

      Background: It has been reported that heart failure is frequently concomitant with sleep disordered breathing (SDB) and hypoxia is a worsening factor of heart failure. The purpose of this study it to evaluate prognostic impact of SDB in patients with acute decompensate heart failure (ADHF). Methods: Consecutive 213 patients (76.3 ± 12.0 years, males, 49.8%) with ADHF emergently admitted to our hospital from September 2015 to March 2017 were enrolled and performed overnight oximetry with PULSOX-Me300 before discharge. We examined and calculated 3% oxygen desaturated index (ODI), and mean SpO2, and defined SDB positive as 3%ODI>15, and low SpO2 as mean SpO2 <95, and investigated prognosis as re-admission of heart failure. Results: 3%ODI was 16.4 ± 12.6 and SDB positive were 96 patients. Median of mean SpO2 was 95.1% (93.8–96.3) and low SpO2 were 106 patients. 44 patients were re-admitted for heart failure, and Kaplan-Meier analysis revealed that low SpO2 group had worse prognosis than normal SpO2 group, on the other hand, SDB positive was not significant (log-rank P = .011 and P = .738, respectively). Conclusions: Low mean SpO2 was associated with increasing risk for re-admission in patients with ADHF.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Cardiac Failure
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect