Background: Mortality is very high in elderly patients with acute myocardial infarction (AMI).
However, the influence on the onset of heart failure (HF) after first-time AMI hasn't
been investigated. Methods: We evaluated 870 consecutive patients admitted with first-time AMI visiting hospital
within 24 hours of onset. Patients were divided into the age groups young: < 60 years,
old: 60 to 80 years, and very old: > 80 years and were evaluated for clinical management
and onset of HF. Results: Those with young, old, and very old comprised 243, 454, and 173 patients, respectively.
As compared with young, old/very old groups were characterized by higher percentage
of female, higher BNP, lower EF and lower rate of revascularization. In-hospital mortality
was significantly high in the very old patients. The symptom-to-door time was the
longest in the very old group. Kaplan-Meier analysis revealed that very old groups
was highest rate of onset of HF. After adjustment with patient background, in comparison
with old group, young group was found to be independently associated with lower rate
of the onset of HF (adjusted HR, 0.30; 95% CI: 0.09 to 0.82, P = .02), while very old group was higher (adjusted HR, 2.58; 95% CI: 1.22–5.39, P = .01). Conclusion: In the very old patients, the risk of development of HF is very high after their
first AMI.
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