Abstract| Volume 23, ISSUE 10, SUPPLEMENT , S35-S36, October 2017

Comparison of Renal Function after Implantation of Continuous-flow and Pulsatile Left Ventricular Assist Devices

      The durability of left ventricular assist device (LVAD) has improved. Both short- and long-term improvement of non-cardiac organs has been described. To date, continuous flow LVAD (CF-LVAD) is the predominant type placed in heart failure patients. The influence of non-pulsatile physiology on the renal function is unknown. The purpose of this study is to compare the renal function after the pulsatile LVAD (P-LVAD) and CF-LVAD support. 40 CF-LVAD patients and 16 P-LVAD patients were included. GFR, BUN, and Cr were assessed. Renal function dramatically improved just after surgery in CF-LVAD patients; however, after that it returned to pre-operative level. In P-LVAD patients, the improved renal function was maintained longer. It is possible that the influence of pulsatile and non-pulsatile physiology on long-term renal function is different.
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