Background: Iron deficiency is associated with poor outcome in chronic HF, but the clinical significance
of iron in ADHF is poorly understood. We examined the impact of iron in ADHF patients.
Methods: We analyzed iron level at discharge in 231 ADHF patients. Patients were divided into
2 groups according to the median iron level. The endpoint was set as the composite
outcome, which included all-cause mortality and readmission for HF. Results: During a mean follow-up of 18.9 months, Kaplan-Meier analysis showed that the incidence
of composite outcome was significantly higher in the low iron group (log-rank P = .0006). The low iron was an independent predictor of composite outcome (HR, 1.50;
95%CI, 1.01–2.25; P = .0428). Conclusions: Low iron at discharge was associated with an increased risk of adverse outcomes in
ADHF patients.
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