A Case of Dramatic Improvement from Cardiomyopathy Induced by Chemotherapy in Patient with Mammalian Carcinoma

Background: Often, we experience cardiovascular disease in patients suffering from cancer. Among them, cardiomyopathy caused by chemotherapy is still a major concern for attending physicians treating cancers. In this time, we demonstrated a case of a woman who dramatically recovered from chemotherapy-induced cardiomyopathy. Case: Eighty-two-year-old women presented to our hospital with breathing difficulty lasting 2 weeks and orthopnea. She had suffered from right mammalian carcinoma. Radiation therapy and some regimens of chemotherapy was performed. After 12 weeks of chemotherapy including Epirubicin and Cyclophosphamide, chest x-ray (CXR) showed pulmonary congestion and effusion, echocardiography (UCG) showed global left ventricular (LV) dysfunction. In addition, cardiac magnetic resonance (CMR) imaging revealed late gadolinium enhancement (LGE) in global mid-ventricle and endocardium. She was diagnosed as chemotherapy-induced cardiomyopathy. We gave angiotensin converting enzyme inhibitor, and β-blocker and diuretics. After treatment, dyspnea and lung congestion in CXR disappeared and LV ejection fraction in UCG improved from 44% to 61%. However, LGE in CMR still remained. She discharged without symptoms. Conclusion: Such a field, Onco-cardiology, is an important field of medicine, and further research will be required. In this time, we show a case of women who dramatically recovered from chemotherapy induced cardiomyopathy.