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Jay N. Cohn New Investigator Award: Basic Science
GLP-1(7-36) and GLP-1(9-36) Protect Murine Hearts from Post-Ischemic Contractile Dysfunction Christopher P. Kolibash, Christine A. Chen, Anbin Mu, Suzanne B. Brown, Richard P. Shannon page S1 Full Text | Full-Text PDF (63 KB)
Mast Cells, the Allergic Responders, a Target of Heart Failure Therapy? Suresh S. Palaniyandi, Kenichi Watanabe, Daria Mochly-Rosen page S1 Full Text | Full-Text PDF (63 KB)
Adoptive Transfer of Regulatory T Cells Protects Against Coxsackievirus-Induced Myocarditis Yu Shi, Masahiro Fukuoka, Guohua Li, Youan Liu, Mayin Chen, Michael Konvisor, Peter P. Liu page S1 Full Text | Full-Text PDF (63 KB)
Cardiac-Specific Overexpression of a Dominant Negative (DN) p67phox Mutant Shows Reduction in Mouse Heart Size Qiong Zhao Dalia Urboniene, Magdalena Ornatowska, R. John Solaro, John W. Christman, Lei Xiao pages S1-S2 Full Text | Full-Text PDF (81 KB)
The Mechanism of Cardiac Failure in Experimental Myocardial Infarction Nicholas T. Befera, Karen R. Wasiluk, James M. Berry, Sylvester Black, Erik G. Strungs, John E. Foker page S2 Full Text | Full-Text PDF (42 KB)
Jay N. Cohn New Investigator Award: Clinical/Integrative Physiology
New Insights into the Effect of Mineralocorticoids on Circulating Progenitor Cell Counts in Canine Models of Cardiovascular Disease: The Case for Accelerated Senescence Barry A. Boilson, Katarina Kontsekova, Josef Korinek, Brian P. Shapiro, Guido Boerrigter, Horng H. Chen, John C. Burnett, Margaret M. Redfield, Robert D. Simari page S3 Full Text | Full-Text PDF (55 KB)
Alpha–1-Adrenergic Receptor Subtypes in Human Heart Failure Brian C. Jensen, Philip Swigart, Marie-Eve Laden, Teresa DeMarco, Charles Hoopes, Paul C. Simpson page S3 Full Text | Full-Text PDF (56 KB)
CYP3A5*1/*3 Genetic Polymorphism Is Associated with Post Cardiac Transplant Renal Dysfunction in Patients Treated with Calcineurin Inhibitors Simon de Denus, Marcin Zakrzewski, Amina Barhdadi, Marie-Helene Leblanc, Normand Racine, Francois Belanger, Michel Carrier, Anique Ducharme, Marie-Pierre Dube, Jacques Turgeon, Michel White page S3 Full Text | Full-Text PDF (56 KB)
Engineered Mutation of Human B-Type Natriuretic Peptide To Preserve Renal Perfusion Pressure Candace Y.W. Lee, John C. Burnett pages S3-S4 Full Text | Full-Text PDF (107 KB)
Prediction of Recovery in Heart Failure with Genomic Biomarkers Bettina Heidecker, Kenneth L. Baughman, Edward K. Kasper, Ilan S. Wittstein, Elayne Breton, Joshua M. Hare page S4 Full Text | Full-Text PDF (72 KB)
Nursing Research Award
The Relationship among Depressive Symptoms, N-Terminal pro B Type Natriuretic Peptide, and Cardiac Events in Patients with Heart Failure Eun Kyeung Song, Debra K. Moser, Misook L. Chung, Seongkum Heo, Terry A. Lennie page S5 Full Text | Full-Text PDF (128 KB)
Living with Advanced Heart Failure: The Patient Experience Bonita L. Huiskes, Kathleen A. Dracup, Maria Gudmundsdottir page S5 Full Text | Full-Text PDF (128 KB)
Factors Influencing Health Status among Thai Patients with Heart Failure Chennet Phonphet, Jom Suwanno, Debra K. Moser page S5 Full Text | Full-Text PDF (128 KB)
Montreal Cognitive Assessment May Be an Appropriate Tool To Assess Cognitive Dysfunction in Heart Failure Ponrathi R. Athilingam, Leway Chen, Kathleen B. King, Michael H. Ackerman pages S5-S6 Full Text | Full-Text PDF (141 KB)
The Advantages and Disadvantages of Heart Failure Disease Management When Randomly Assigned To Be Delivered by Telehealth or Telephone Kathryn H. Bowles, David A. Horowitz page S6 Full Text | Full-Text PDF (36 KB)
Oral Presentations: Leading Clinical Research
How Often Does Cardiotoxicity Lead to Discontinuation of Trastuzumab? Gregory R. Hartlage, Ren Chen, Maya E. Guglin page S7 Full Text | Full-Text PDF (50 KB)
Can the Seattle Heart Failure Model Be Used to Risk Stratify Patients for an LVAD: Application to REMATCH Patients Wayne C. Levy, Dariush Mozaffarian, David T. Linker, David Farrar, Leslie W. Miller page S7 Full Text | Full-Text PDF (50 KB)
Features and Hospital Outcomes for Nonadherent Patients with Heart Failure: Findings from GWTG-HF Amrut V. Ambardekar, Wenqin Pan, Steven L. Peterson, Gregg C. Fonarow, Laura E. Webb, Adrian F. Hernandez, Christopher P. Cannon, Eric D. Peterson, Mori J. Krantz page S7 Full Text | Full-Text PDF (50 KB)
Weekend Hospital Admission for Heart Failure: Influence on Quality of Care, Length of Stay, and In-Hospital Mortality Tamara B. Horwich Gregg C. Fonarow, Kenneth A. LaBresh, Clyde Yancy, Nancy M. Albert, Adrian F. Hernandez, Li Liang, GWTG Steering Committee and Hospitals pages S7-S8 Full Text | Full-Text PDF (128 KB)
Human Myocardial b1 389 Arg/Arg Adrenergic Receptors Exhibit a Propensity for Constitutively Active, High Affinity Agonist Binding and Are Selectively Inactivated by Bucindolol Ryan Walsh, Ryan Farmer, Mara Kelly, Penny Blain-Nelson, Jennifer Morrison, J. David Port, Michael R. Bristow page S8 Full Text | Full-Text PDF (104 KB)
Gene Variants in Caveolin-1 and Caveolin-2 in Patients with Idiopathic Pulmonary Arterial Hypertension Christian Zellner, Wilson Liao, Clive R. Pullinger, Annie Poon, Pui Kwok, Mary J. Malloy, John P. Kane, Dana McGlothlin, Kanu Chatterjee, Teresa DeMarco page S8 Full Text | Full-Text PDF (104 KB)
Action Potential Dynamics Explain Arrhythmic Susceptibility in Systolic Heart Failure Gautam G. Lalani, Jason Bayer, Natalia A. Trayanova, Sanjiv M. Narayan pages S8-S9 Full Text | Full-Text PDF (112 KB)
The B-Type Natriuretic Peptide T–381C Polymorphism Is Associated with Increased BNP Plasma Immunoreactivity and Higher Prevalence of Type 2 Diabetes Mellitus and Atrial Fibrillation Lisa C. Costello-Boerrigter, Guido Boerrigter, Syed Ameenuddin, Timothy M. Olson, Margaret M. Redfield, Richard J. Rodeheffer, Denise M. Heublein, John C. Burnett page S9 Full Text | Full-Text PDF (32 KB)
Cardiovascular Physiology
Myocardial Relaxation and Stiffness Are Different across Ejection Fraction in Heart Failure with Preserved Ejection Fraction Rodolphe P. Katra, Yi-Chih Wang, Chih-Chieh Yu, Kathryn Hilpisch, Jiunn-Lee Lin page S10 Full Text | Full-Text PDF (56 KB)
Speckle Tracking Strain Echocardiography Quantifies Diastolic Function and Its Improvement with Exercise Training Mark A. Trimble, Stephen Hsu, David Adams, Gregory Samsa, William Kraus, Pamela Douglas page S10 Full Text | Full-Text PDF (56 KB)
Coupled Pacing Does Not Impair Heart Rate Response to Exercise Ruth N. Klepfer, James H. Baker, Andrew D. Merliss, Mark W. Preminger, Mark F. Aaron, Steve Krueger, Ronald S. Freudenberger page S10 Full Text | Full-Text PDF (56 KB)
Mechanical Dyssynchrony in Advanced Decompensated Heart Failure: Relation to Hemodynamic Responses to Intensive Medical Therapy Wilfried Mullens, Allan G. Borowski, Richard A. Grimm, James D. Thomas, Wilson H.W. Tang pages S10-S11 Full Text | Full-Text PDF (129 KB)
Renal Cyclic GMP Stimulating Actions of a Novel Chimeric Natriuretic Peptide CD-NP in Isolated Glomeruli: Evidence for NPR-A Activation Candace Y.W. Lee, Sharon S.M. Sandberg, Horng H. Chen, Ondrej Lisy, John C. Burnett page S11 Full Text | Full-Text PDF (98 KB)
Nesiritide Acutely Prolongs Electromechanical Activation Time, a Non-Invasive Acoustic Cardiographic Marker of Contractility, in Heart Failure Patients Shadi M. Karabsheh, Andrew D. Michaels page S11 Full Text | Full-Text PDF (98 KB)
Direct Inotropic Effects of Exogenous and Endogenous Urotensin-II: Divergent Actions in Failing and Non-Failing Human Myocardium Michael P. Quaile, Hajime Kubo, Stephen A. Douglas, Kenneth B. Margulies pages S11-S12 Full Text | Full-Text PDF (440 KB)
Cardiac beta3-Adrenergic Receptor: A New Target for the Treatment of Exercise Intolerance in Heart Failure Che-Ping Cheng, Satoshi Masutani, Heng-Jie Cheng, Atsushi Morimoto, Hiroshi Hasegawa, William C. Little page S12 Full Text | Full-Text PDF (366 KB)
Heart Failure with Preserved Ejection Fraction Patients Have Significantly Heterogeneous Demographic, Cardiac and Functional Manifestations of HF Yi-Chih Wang, Chih-Chieh Yu, Kathryn Hilpisch, Rodolphe P. Katra, Jiunn-Lee Lin page S12 Full Text | Full-Text PDF (366 KB)
Cardiac Physiologic Effects of Biventricular Pacemaker Optimization in Patients with Heart Failure Tasneem Z. Naqvi, Jing Zhang pages S12-S13 Full Text | Full-Text PDF (607 KB)
Electro-Mechanical Delay and Uncoupling Are Major Determinants of Dysfunction in Heart Failure with Preserved Ejection Fraction Rodolphe P. Katra, Yi-Chih Wang, Chih-Chieh Yu, Kathryn Hilpisch, Jiunn-Lee Lin page S13 Full Text | Full-Text PDF (266 KB)
Sleep Disorder Breathing Is Very Prevalent during Heart Failure Exacerbations and Represents a Unique Therapeutic Target Darshak H. Karia, Mohammad Z. Hoque, Nazmul Huda, Hong Ra, Roger Ishac pages S13-S14 Full Text | Full-Text PDF (306 KB)
Interaction between Mineralocorticoid Receptor Activation and Pressure Overload: Implications for Systolic and Diastolic Function Selma F. Mohammed, Josef Korinek, Carolyn S. Lam, Margaret M. Redfield page S14 Full Text | Full-Text PDF (65 KB)
Impact of Reductions in Aortic Pressure Augmentation on Stroke Volume and Diastolic Function in Elderly Subjects Nancy K. Sweitzer, Joseph H. Skalski, Kevin L. Eggleston, Colette A. Wagner, Mauricio Velez, Gary F. Mitchell page S14 Full Text | Full-Text PDF (65 KB)
Right Ventricular Pressure Patterns Prior to Heart Failure Hospitalizations in Patients with Systolic or Diastolic Heart Failure Michael R. Zile, Philip B. Adamson, Robert C. Bourge, Yong K. Cho, Tom D. Bennett page S14 Full Text | Full-Text PDF (65 KB)
Depressed Myocardial Contractility Despite Normal Chamber Systolic Function in Heart Failure with Preserved Ejection Fraction Carolyn S.P. Lam, Barry A. Borlaug, Veronique L. Roger, Richard J. Rodeheffer, Josef Korinek, Margaret M. Redfield pages S14-S15 Full Text | Full-Text PDF (139 KB)
Effects of Inhibition of AGE-RAGE Interaction in Pressure-Overload Hypertrophy by Treatment with sRAGE Catalin F. Baicu, Amy D. Bradshaw, Janet M. Boggs, Tyler J. Rentz, An O. Van Laer, Mark S. Kindy, Michael R. Zile page S15 Full Text | Full-Text PDF (98 KB)
Serial Examination of Sarcoplasmic Reticulum Function in Cardiac Hypertrophy Due to Pressure Overload Peter Wojciechowski, Danijel Juric, Xinghai Yao, Satyajeet Rathi, Thomas Netticadan page S15 Full Text | Full-Text PDF (98 KB)
Non-Invasive Measurement of Cardiac Performance in Recovery from Exercise in Heart Failure Jonathan Myers, Pradeep Gujja, Suresh Neelagaru, Leon Hsu, Daniel Burkhoff page S15 Full Text | Full-Text PDF (98 KB)
Periodic Breathing during Wakefulness in Cardiac Resynchronization Therapy: Can It Predict Outcome? Alaa Shalaby, Charles Atwood, Faith Selzer, Refaat Marwan, John Gorcsan, Patrick Strollo pages S15-S16 Full Text | Full-Text PDF (123 KB)
Transition from Asymptomatic to Overt Systolic Heart Failure – Renal, Hemodynamic and Neurohumoral Adaptations Josef Korinek, Alessandro Cataliotti, Horng H. Chen, Guido Boerrigter, Martin Fernando, Margaret M. Redfield, Tracy L. Stevens, John C. Burnett page S16 Full Text | Full-Text PDF (50 KB)
Soluble and Particulate Guanylate Cyclase Differentially Affect Cyclic Guanosine Monophosphate in Plasma and Urine Guido Boerrigter, Lisa C. Costello-Boerrigter, Harald Lapp, Johannes-Peter Stasch, John C. Burnett page S16 Full Text | Full-Text PDF (50 KB)
Prevalence and Prognostic Significance of Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction: A Population-Based Study Carolyn S.P. Lam, Veronique L. Roger, Richard R. Rodeheffer, Barry A. Borlaug, Margaret M. Redfield pages S16-S17 Full Text | Full-Text PDF (132 KB)
Kidney-Heart Connection: Experimental Mild Renal Insufficiency Induces Early Cardiac Fibrosis and Myocardial Diastolic Dysfunction Followed by Late Systolic Failure Fernando L. Martin, Josef Korinek, Brenda K. Huntley, Elise A. Oehler, Gerald E. Harders, Alessandro Cataliotti, Horng H. Chen, John C. Burnett page S17 Full Text | Full-Text PDF (106 KB)
Regional Right Ventricular Myocardial Strain by Echocardiographic Speckle Tracking Distinguishes Clinical and Hemodynamic RV Dysfunction in Pulmonary Hypertension Manuela Reali, Navin Rajagopalan, Angel Lopez-Candales, Kevin E. Cordero, Matthew Suffoletto, Sanjeev G. Shroff, Michael R. Pinsky, John Gorcsan, Michael A. Mathier, Marc A. Simon page S17 Full Text | Full-Text PDF (106 KB)
Abnormal Contractile Reserve Limits Exercise Capacity in Heart Failure with Preserved EF Barry A. Borlaug, Thomas P. Olson, Kelly S. Flood, Bruce D. Johnson, Margaret M. Redfield page S17 Full Text | Full-Text PDF (106 KB)
The Lowest VE/VCO2 Ratio during Exercise as a Predictor of Outcomes in Patients with Heart Failure Jonathan Myers, Ross Arena, Ricardo Oliviera, Daniel Bensimhon, Joshua Abella, Leon Hsu, Paul Chase, Marco Guazzi, Mary Ann Peberdy pages S17-S18 Full Text | Full-Text PDF (218 KB)
Experimental Cancer Cachexia Severely Impairs Heart Function Jochen Springer, Sandra Palus, Mathias Rauchhaus, Stefan D. Anker page S18 Full Text | Full-Text PDF (135 KB)
Determination of Cardiac Output by Impedance Cardiography: A Comparison with Cardiovascular Magnetic Resonance as a Gold-Standard Humberto Villacorta, Clerio Azevedo, Marcelo Hadlich, Fernanda Amador, Sabrina Bezerra, Mariane Spotti page S18 Full Text | Full-Text PDF (135 KB)
Accuracy of Respiration Rate Trends from an Implanted CRM Device John D. Hatlestad, Yi Zhang, Ron D.B. Simon, Alaa A. Shalaby pages S18-S19 Full Text | Full-Text PDF (426 KB)
Significant Sleep Disordered Breathing Occurs during Non-Traditional Sleep Hours as Well as Traditional Sleeping Time in Patients Hospitalised with Acute Heart Failure Exacerbation Darshak H. Karia, Nazmul Huda, Mohammad Z. Hoque, Hong Ra, Roger Ishac page S19 Full Text | Full-Text PDF (313 KB)
Sleep Disordered Breathing during Acute Heart Failure Hospitalization Does Not Resolve Despite Standard Guideline Based Medical Therapy Admission Darshak H. Karia, Mohammad Hoque, Nazmul Huda, Hong Ra, Roger Ishac page S19 Full Text | Full-Text PDF (313 KB)
The Effect of QRS Duration on Peak Systolic Intraventricular Velocities by Tissue Doppler Imaging Sameer J. Khandhar, Angel Lopez-Candales pages S19-S20 Full Text | Full-Text PDF (467 KB)
Utility of Continuous Body Temperature Monitoring in Predicting Prognosis in Cardiomyopathic Hamsters Amany Ahmed Sreedevi Gondi, Muhammad Munir, Casey Cox, K.J. Shankar, Igor Stupin, Ed Sobash, Sabrina Engel, Shubha Asopa, Dejian Lai, Alan Brewer, James Wilson, S. Ward Casscells page S20 Full Text | Full-Text PDF (177 KB)
Acute and Chronic Hemodynamic Effects of Biventricular Pacing in Patients with Coronary Artery Disease and Lateral LV Wall Infarct Dusan Kocovic, Nancy Britton, Scott Cox, Mark Heimann, Glen Miske, Steven Rothman page S20 Full Text | Full-Text PDF (177 KB)
Resting Heart Rate Does Not Reflect the Degree of beta–1 Receptor Sensitivity in Subjects with Heart Failure on Chronic Beta Blocker Therapy Andrea Mignatti, Gabriel Sayer, Ulrich P. Jorde pages S20-S21 Full Text | Full-Text PDF (261 KB)
Serum Protein Carbonyl Level Is Higher in AL Amyloidosis Patients Versus Healthy Controls – Evidence of Systemic Oxidative Stress Megan Bright, Parameswaran Hari, Seth Truran, Jingli Wang, David D. Gutterman, Raymond Q. Migrino page S21 Full Text | Full-Text PDF (108 KB)
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