Journal of Cardiac Failure
Volume 16, Issue 12 , Pages 980-990 , December 2010

Thrombomodulin is Upregulated in Cardiomyocytes During Cardiac Hypertrophy and Prevents the Progression of Contractile Dysfunction

  • Yi-Heng Li, MD, PhD

      Affiliations

    • Department of Internal Medicine, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Corresponding Author InformationReprint requests: Yi-Heng Li, MD, PhD, Department of Internal Medicine, National Cheng Kung University Hospital, 138 Sheng Li Road, Tainan 704, Taiwan. Tel: +886-6-2353535 ext 2392; Fax: +886-6-2753834.
  • ,
  • Hsing-Chun Chung, MS

      Affiliations

    • Department of Internal Medicine, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
  • ,
  • Chawn-Yau Luo, MD

      Affiliations

    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Department of Surgery, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
  • ,
  • Ting-Hsing Chao, MD

      Affiliations

    • Department of Internal Medicine, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
  • ,
  • Kou-Gi Shyu, MD, PhD

      Affiliations

    • Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
  • ,
  • Guey-Yueh Shi, PhD

      Affiliations

    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • ,
  • Hua-Lin Wu, PhD

      Affiliations

    • Cardiovascular Research Center, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    • Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Received 12 February 2010 ,Revised 13 May 2010 ,Accepted 16 June 2010.

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 This work was supported by grants NSC96-2314-B-006-063-MY2, NSC98-2314-B-006-050-MY2, and NSC 96-2752-B-006-005-PAE from the National Science Council, Taipei, Taiwan and grants NCKUH-9701006 and 9802009 from the National Cheng Kung University Hospital, Tainan, Taiwan.

 See page 989 for disclosure information.

PII: S1071-9164(10)00713-X

doi: 10.1016/j.cardfail.2010.06.415

Journal of Cardiac Failure
Volume 16, Issue 12 , Pages 980-990 , December 2010