Journal of Cardiac Failure
Volume 16, Issue 9 , Pages 709-713 , September 2010

Addition of a Second LV Pacing Site in CRT Nonresponders Rationale and Design of the Multicenter Randomized V3 Trial

  • Pierre Bordachar, MD

      Affiliations

    • Hopital Haut Leveque, Pessac, France
    • Corresponding Author InformationReprint requests: Pierre Bordachar, MD, Hospital Haut Leveque, Service Pr. Clementy, Pessac 33604, France. Tel: 33 5 57 65 65 65; Fax: 33 5 57 65 65 09.
    • ,
  • Christine Alonso, MD

      Affiliations

    • Clinique Medico-chirurgicale Bizet, Paris, France
    • ,
  • Frederic Anselme, MD

      Affiliations

    • CHU Charles Nicolle, Rouen, France
    • ,
  • Serge Boveda, MD

      Affiliations

    • Clinique Pasteur, Toulouse, France
    • ,
  • Pascal Defaye, MD

      Affiliations

    • CHU Grenoble, La Tronche, France
    • ,
  • Stephane Garrigue, MD

      Affiliations

    • CliniqueSaint Augustin, Bordeaux, France
    • ,
  • Daniel Gras, MD

      Affiliations

    • Nouvelles Cliniques Nantaises, Nantes, France
    • ,
  • Didier Klug, MD

      Affiliations

    • CHRU Lille, Lille, France
    • ,
  • Olivier Piot, MD

      Affiliations

    • Centre Cardiologique du Nord, Saint Denis, France
    • ,
  • Nicolas Sadoul, MD

      Affiliations

    • CHU de Brabois, Vandoeuvre les Nancy, France
    • ,
  • Christophe Leclercq, MD

      Affiliations

    • CHU Pontchaillou, Rennes, France

Received 24 February 2010 ,Revised 21 April 2010 ,Accepted 29 April 2010.

References 

  1. Abraham WT, Fisher WG, Smith AL, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002;346:1845–1853
  2. Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350:2140–2150
  3. Cleland JG, Daubert JC, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539–1549
  4. Chung SE, Leon AR, Tavazzi L, et al. Results of the predictors of response to CRT (PROSPECT) trial. Circulation. 2008;117:2608–2616
  5. Yu CM, Fung WH, Lin H, et al. Predictors of left ventricular reverse remodeling after cardiac resynchronization therapy for heart failure secondary to idiopathic dilated or ischemic cardiomyopathy. Am J Cardiol. 2003;91:684–688
  6. Bax JJ, Marwick TH, Molhoek SG, et al. Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation. Am J Cardiol. 2003;92:1238–1240
  7. Leclercq C, Gadler F, Kranig W, et al. A randomized comparison of triple-site versus dual-site ventricular stimulation in patients with congestive heart failure. J Am Coll Cardiol. 2008;51:1455–1462
  8. Lenarczyk R, Kowalski O, Kukulski T, et al. Triple-site biventricular pacing in patients undergoing cardiac resynchronization therapy: a feasibility study. Europace. 2007;9:762–767
  9. Packer M. Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure. J Card Fail. 2001;7:176–182
  10. Jessup M, Abraham WT, Casey DE, et al. 2009 focused update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation. 2009;119:1977–2016
  11. Ypenburg C, van Bommel RJ, Borleffs CJ, et al. Long-term prognosis after cardiac resynchronization therapy is related to the extent of left ventricular reverse remodeling at midterm follow-up. J Am Coll Cardiol. 2009;53:483–490

 See page 712 for disclosure information.

PII: S1071-9164(10)00202-2

doi: 10.1016/j.cardfail.2010.04.010

Journal of Cardiac Failure
Volume 16, Issue 9 , Pages 709-713 , September 2010

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