Journal of Cardiac Failure
Volume 16, Issue 5 , Pages 390-395 , May 2010

Lower Extremity Performance Measures Predict Long-Term Prognosis in Older Patients Hospitalized for Heart Failure

  • Daniela Chiarantini, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Stefano Volpato, MD, MPH

      Affiliations

    • Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy
  • ,
  • Fotini Sioulis, MD

      Affiliations

    • Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy
  • ,
  • Francesca Bartalucci, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Laura Del Bianco, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Irene Mangani, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Giuseppe Pepe, MD

      Affiliations

    • Emergency Department, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Francesca Tarantini, MD, PhD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Andrea Berni, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Internal Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Niccolo Marchionni, MD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
  • ,
  • Mauro Di Bari, MD, PhD

      Affiliations

    • Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • Corresponding Author InformationReprint requests: Mauro Di Bari, MD, PhD, Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics Medicine, University of Florence, Viale Pieraccini, 650139 Florence-Italy. Tel: +39 055 4271468; Fax: +39 055 4271469.

Received 4 October 2009 ,Revised 12 January 2010 ,Accepted 19 January 2010.

References 

  1. Davies M, Hobbs F, Davis R, Kenkre J, Roalfe AK, Hare R, et al. Prevalence of left-ventricular systolic dysfunction and heart failure in the Echocardiographic Heart of England Screening study: a population based study. Lancet. 2001;358:439–444
  2. Di Bari M, Pozzi C, Cavallini MC, Innocenti F, Baldereschi G, De Alfieri W, et al. The diagnosis of heart failure in the community. Comparative validation of four sets of criteria in unselected older adults: the ICARe Dicomano Study. J Am Coll Cardiol. 2004;44:1601–1608
  3. Zuccala G, Cattel C, Manes-Gravina E, Di Niro MG, Cocchi A, Bernabei R. Left ventricular dysfunction: a clue to cognitive impairment in older patients with heart failure. J Neurol Neurosurg Psychiatry. 1997;63:509–512
  4. Kattainen A, Koskinen S, Reunanen A, Martelin T, Knekt P, Aromaa A. Impact of cardiovascular diseases on activity limitations and need for help among older persons. J Clin Epidemiol. 2004;57:82–88
  5. Parmley WW. Do we practice geriatric cardiology?. J Am Coll Cardiol. 1997;29:217–218
  6. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85–M94
  7. Guralnik JM, Ferrucci L, Simonsick E, Salive ME, Wallace RB. Lower-extremity function in persons over the age of 70 years as predictor of subsequent disability. N Engl J Med. 1995;332:556–561
  8. Di Bari M, Virgillo A, Matteuzzi D, Inzitari M, Mazzaglia G, Pozzi C, et al. Predictive validity of measures of comorbidity in older community dwellers: the Insufficienza Cardiaca negli Anziani Residenti a Dicomano Study. J Am Geriatr Soc. 2006;54:210–216
  9. Studenski S, Perera S, Wallace D, Chandler JM, Duncan PW, Rooney E, et al. Physical performance measures in the clinical setting. J Am Geriatr Soc. 2003;51:314–322
  10. Volpato S, Cavalieri M, Guerra G, Sioulis F, Ranzini M, Maraldi C, et al. Performance-based functional assessment in older hospitalized patients: feasibility and clinical correlates. J Gerontol A Biol Sci Med Sci. 2008;63:1393–1398
  11. Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. J Am Coll Cardiol. 2009;53:e1–e90
  12. Heikkinen E, Waters WE, Brzezinski ZJ. The elderly in eleven countries. A socio-medical survey. WHO Regional Office for Europe Edt., editor. WHO, Public Health in Europe 21. 1983. Copenhagen.
  13. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982;17:37–49
  14. Kohout FJ, Berkman LF, Evans DA, Cornoni-Huntley J. Two shorter forms of the CES-D (Center for Epidemiological Studies Depression) depression symptoms index. J Aging Health. 1993;5:179–193
  15. Linn BS, Linn MW, Gurel L. Cumulative illness rating scale. J Am Geriatr Soc. 1968;16:622–626
  16. Sahn DJ, De Maria AN, Kisslo J, Weiman A. The Committee on M-mode Standardization of the American Society of Echocardiography. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978;58:1072–1083
  17. Di Bari M, Balzi D, Roberts AT, Barchielli A, Fumagalli S, Ungar A, et al. Prognostic stratification of older persons based on simple administrative data: development and validation of the “silver code,” to be used in emergency department triage. J Gerontol A Biol Sci Med Sci. 2010;65:159–164
  18. Purser JL, Weinberger M, Cohen HJ, Pieper CF, Morey MC, Li T, et al. Walking speed predicts health status and hospital costs for frail elderly male veterans. J Rehabil Res Dev. 2005;42:535–546
  19. Volpato S, Onder G, Cavalieri M, Guerra G, Sioulis F, Maraldi C, et al. Characteristics of nondisabled older patients developing new disability associated with medical illnesses and hospitalization. J Gen Intern Med. 2007;22:668–674
  20. Hunt SA, Baker DW, Chin MH, Cinquegrani MP, Feldman AM, Francis GS, et al. ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1995 Guidelines for the Evaluation and Management of Heart Failure). J Am Coll Cardiol. 2001;38:2101–2113
  21. Cacciatore F, Abete P, Ferrara N, Paolisso G, Amato L, Canonico S, et al. The role of blood pressure in cognitive impairment in an elderly population. Osservatorio Geriatrico Campano Group. J Hypertens. 1997;15:135–142
  22. Ingle L. Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure. Eur J Heart Fail. 2008;10:112–118
  23. Ingle L, Shelton RJ, Rigby AS, Nabb S, Clark AL, Cleland JG. The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure. Eur Heart J. 2005;26:1742–1751
  24. Rostagno C, Olivo G, Comeglio M, Boddi V, Banchelli M, Galanti G, et al. Prognostic value of 6-minute walk corridor test in patients with mild to moderate heart failure: comparison with other methods of functional evaluation. Eur J Heart Fail. 2003;5:247–252
  25. Ingle L, Rigby AS, Carroll S, Butterly R, King RF, Cooke CB, et al. Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure. Eur Heart J. 2007;28:560–568
  26. Lucas C, Stevenson LW, Johnson W, Hartley H, Hamilton MA, Walden J, et al. The 6-min walk and peak oxygen consumption in advanced heart failure: aerobic capacity and survival. Am Heart J. 1999;138:618–624
  27. Clark AL. Origin of symptoms in chronic heart failure. Heart. 2006;92:12–16
  28. Brinkley TE, Leng X, Miller ME, Kitzman DW, Pahor M, Berry MJ, et al. Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci. 2009;64:455–461
  29. Pahor M, Blair SN, Espeland M, Fielding R, Gill TM, Guralnik JM, et al. Effects of a physical activity intervention on measures of physical performance: results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci. 2006;61:1157–1165
  30. Kitzman DW. Diastolic heart failure in the elderly. Heart Fail Rev. 2002;7:17–27
  31. Kannel WB, Belanger AJ. Epidemiology of heart failure. Am Heart J. 1991;121:951–957
  32. Ho KKL, Pinsky JL, Kannel WB, Levy D. The epidemiology of heart failure: the Framingham study. J Am Coll Cardiol. 1993;22(Suppl A):6A–13A

 Conflict of interest: none.

PII: S1071-9164(10)00018-7

doi: 10.1016/j.cardfail.2010.01.004

Journal of Cardiac Failure
Volume 16, Issue 5 , Pages 390-395 , May 2010