Journal of Cardiac Failure
Volume 16, Issue 5 , Pages 374-380 , May 2010

Renal Function in Outpatients With Chronic Heart Failure

  • Bård Waldum, MD

      Affiliations

    • Department of Nephrology, Ullevål University Hospital, Oslo, Norway
    • Corresponding Author InformationReprint requests: Bård Waldum, MD, Department of Nephrology, Ullevål University Hospital, N-0407 Oslo, Norway. Tel: +47 22 11 91 00; Fax: +47 23 01 59 50.
  • ,
  • Arne S. Westheim, MD, PhD

      Affiliations

    • Department of Cardiology, Ullevål University Hospital, Oslo, Norway
  • ,
  • Leiv Sandvik, PhD

      Affiliations

    • Department of Biostatistics, Ullevål University Hospital, Oslo, Norway
  • ,
  • Berit Flønæs, RN

      Affiliations

    • Department of Medicine, Asker and Bærum Health Authority, Sandvika, Norway
  • ,
  • Morten Grundtvig, MD

      Affiliations

    • Department of Medicine, Innlandet Hospital Trust, Lillehammer, Norway
  • ,
  • Lars Gullestad, MD, PhD

      Affiliations

    • Department of Cardiology, Rikshospitalet University Clinic, Oslo, Norway
  • ,
  • Torstein Hole, MD, PhD

      Affiliations

    • Norwegian University of Science and Technology, Trondheim, Norway
    • Department of Medicine, Ålesund Hospital, Helse Sunnmøre HF, Ålesund, Norway
  • ,
  • Ingrid Os, MD, PhD

      Affiliations

    • Department of Nephrology, Ullevål University Hospital, Oslo, Norway
    • Faculty of Medicine, University of Oslo, Norway

Received 8 January 2009 ,Revised 4 January 2010 ,Accepted 12 January 2010.

References 

  1. Kannel WB. Incidence and epidemiology of heart failure. Heart Fail Rev. 2000;5:167–173
  2. Bleumink GS, Knetsch AM, Sturkenboom MC, Straus SM, Hofman A, Deckers JW, et al. Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study. Eur Heart J. 2004;25:1614–1619
  3. de Silva R, Nikitin NP, Witte KK, Rigby AS, Goode K, Bhandari S, et al. Incidence of renal dysfunction over 6 months in patients with chronic heart failure due to left ventricular systolic dysfunction: contributing factors and relationship to prognosis. Eur Heart J. 2006;27:569–581
  4. Hillege HL, Girbes AR, de Kam PJ, Boomsma F, de Zeeuw D, Charlesworth A, et al. Renal function, neurohormonal activation, and survival in patients with chronic heart failure. Circulation. 2000;102:203–210
  5. Hillege HL, Nitsch D, Pfeffer MA, Swedberg K, McMurray JJ, Yusuf S, et al. Renal function as a predictor of outcome in a broad spectrum of patients with heart failure. Circulation. 2006;113:671–678
  6. McClellan WM, Langston RD, Presley R. Medicare patients with cardiovascular disease have a high prevalence of chronic kidney disease and a high rate of progression to end-stage renal disease. J Am Soc Nephrol. 2004;15:1912–1919
  7. Cohen N, Gorelik O, Moznino-Sarafian D, Alon I, Tourovski Y, Weissgarten J, et al. Renal dysfunction in congestive heart failure, pathophysiological and prognostic significance. Clin Nephrol. 2004;61:177–184
  8. McAlister FA, Ezekowitz J, Tonelli M, Armstrong PW. Renal insufficiency and heart failure: prognostic and therapeutic implications from a prospective cohort study. Circulation. 2004;109:1004–1009
  9. Damman K, Navis G, Voors AA, Asselbergs FW, Smilde TD, Cleland JG, et al. Worsening renal function and prognosis in heart failure: systematic review and meta-analysis. J Card Fail. 2007;13:599–608
  10. Ronco C, Haapio M, House AA, Anavekar N, Bellomo R. Cardiorenal syndrome. J Am Coll Cardiol. 2008;52:1527–1539
  11. De Santo NG, Cirillo M, Perna A, Pollastro RM, Frangiosa A, Di SE, et al. The kidney in heart failure. Semin Nephrol. 2005;25:404–407
  12. Ezekowitz J, McAlister FA, Humphries KH, Norris CM, Tonelli M, Ghali WA, et al. The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease. J Am Coll Cardiol. 2004;44:1587–1592
  13. Remme WJ, Swedberg K. Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J. 2001;22:1527–1560
  14. Rustad P, Felding P, Franzson L, Kairisto V, Lahti A, Martensson A, et al. The Nordic Reference Interval Project 2000: recommended reference intervals for 25 common biochemical properties. Scand J Clin Lab Invest. 2004;64:271–284
  15. Khan NA, Ma I, Thompson CR, Humphries K, Salem DN, Sarnak MJ, et al. Kidney function and mortality among patients with left ventricular systolic dysfunction. J Am Soc Nephrol. 2006;17:244–253
  16. Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999;341:709–717
  17. Tamirisa KP, Aaronson KD, Koelling TM. Spironolactone-induced renal insufficiency and hyperkalemia in patients with heart failure. Am Heart J. 2004;148:971–978
  18. Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. Circulation. 1990;82:1730–1736
  19. Eshaghian S, Horwich TB, Fonarow GC. Relation of loop diuretic dose to mortality in advanced heart failure. Am J Cardiol. 2006;97:1759–1764
  20. Ikram H, Chan W, Espiner EA, Nicholls MG. Haemodynamic and hormone responses to acute and chronic frusemide therapy in congestive heart failure. Clin Sci (Lond). 1980;59:443–449
  21. Galve E, Mallol A, Catalan R, Palet J, Mendez S, Nieto E, et al. Clinical and neurohumoral consequences of diuretic withdrawal in patients with chronic, stabilized heart failure and systolic dysfunction. Eur J Heart Fail. 2005;7:892–898
  22. Remuzzi G, Perico N, Macia M, Ruggenenti P. The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease. Kidney Int Suppl. 2005;99:S57–S65
  23. de Silva R, Rigby AS, Witte KK, Nikitin NP, Tin L, Goode K, et al. Anemia, renal dysfunction, and their interaction in patients with chronic heart failure. Am J Cardiol. 2006;98:391–398
  24. Silva RP, Barbosa PH, Kimura OS, Sobrinho CR, Sousa Neto JD, Silva FA, et al. Prevalance of anemia and its association with cardio-renal syndrome. Int J Cardiol. 2007;120:232–236
  25. Go AS, Yang J, Ackerson LM, Lepper K, Robbins S, Massie BM, et al. Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation. 2006;113:2713–2723
  26. Rossert JA, McClellan WM, Roger SD, Verbeelen DL, Horl WH. Contribution of anemia to progression of renal disease: a debate. Nephrol Dial Transplant. 2002;17(Suppl 1):60–66
  27. Smilde TD, van Veldhuisen DJ, Navis G, Voors AA, Hillege HL. Drawbacks and prognostic value of formulas estimating renal function in patients with chronic heart failure and systolic dysfunction. Circulation. 2006;114:1572–1580

 Conflict of interest: none

PII: S1071-9164(10)00015-1

doi: 10.1016/j.cardfail.2010.01.001

Journal of Cardiac Failure
Volume 16, Issue 5 , Pages 374-380 , May 2010