Journal of Cardiac Failure
Volume 16, Issue 4 , Pages 314-319, April 2010

A Promoter Polymorphism of the Endothelial Nitric Oxide Synthase Gene is Associated With Reduced mRNA and Protein Expression in Failing Human Myocardium

  • Amit A. Doshi, MD

      Affiliations

    • Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH
    • Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH
    • ,
  • Mark T. Ziolo, PhD

      Affiliations

    • Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH
    • Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH
    • ,
  • Honglan Wang, PhD

      Affiliations

    • Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH
    • Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH
    • ,
  • Emily Burke, RN, BSN, CCTC

      Affiliations

    • Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH
    • ,
  • Amanda Lesinski, BS

      Affiliations

    • Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH
    • ,
  • Philip Binkley, MD, MPH

      Affiliations

    • Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH
    • Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH
    • Corresponding Author InformationReprint requests: Philip F. Binkley, MD, MPH, Wilson Professor of Medicine, Professor of Epidemiology, Vice Chair for Academic Affairs, The Ohio State University, Room 221 Means Hall, 1654 Upham Drive, Columbus, OH 43210. Tel: 614-293-8963; Fax: 614-293-5614

Received 2 June 2009; received in revised form 8 December 2009; accepted 17 December 2009. published online 08 February 2010.

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 Dr. Philip F. Binkley is supported by National Heart, Lung and Blood Institute/National Institutes of Health Grant K24-HL04208 and the James H. and Ruth J. Wilson Professorship. Dr. Ziolo is supported by National Institutes of Health Grant HL079283 and HLO94692. Dr. Wang is supported by The American Heart Association Post-Doctoral Fellowship 0725560B.

PII: S1071-9164(09)01233-0

doi:10.1016/j.cardfail.2009.12.013

Journal of Cardiac Failure
Volume 16, Issue 4 , Pages 314-319, April 2010

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