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Journal of Cardiac Failure
Volume 16, Issue 3
, Pages 207-210
, March 2010
Metformin Use in Patients With Diabetes Mellitus and Heart Failure: Friend or Foe?
References
- . The incidence of congestive heart failure in type 2 diabetes: an update. Diabetes Care. 2004;27:1879–1884
- Glycemic status and incident heart failure in elderly without history of diabetes mellitus: the health, aging, and body composition study. J Card Fail. 2009;15:593–599
- . The association of heart failure with insulin resistance and the development of type 2 diabetes. Am J Hypertens. 2005;18:731–737
- . Diabetes mellitus and congestive heart failure. Further knowledge needed. Eur Heart J. 1999;20:789–795
- Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005;149:209–216
- Impact of diabetes mellitus on long-term survival in patients with congestive heart failure. Eur Heart J. 2004;25:656–662
- . Prognostic impact of diabetes mellitus in patients with heart failure according to the etiology of left ventricular systolic dysfunction. J Am Coll Cardiol. 2001;38:421–428
- Standards of Medical Care in Diabetes—2009. Diabetes Care. 2009;32(Suppl 1):S13–S61
- . Relationship of hemoglobin A1C and mortality in heart failure patients with diabetes. J Am Coll Cardiol. 2009;54:422–428
- . Aiming for the best control of glycemia in patients with heart failure and type 2 diabetes the “sweet spot”. J Am Coll Cardiol. 2009;54:429–431
- . Relationship between heart failure and lipids: the paradigm continues to evolve. J Card Fail. 2007;13:254–258
- . Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes. Diabetes Care. 2002;25:2244–2248
- . Reduced cardiovascular morbidity and mortality associated with metformin use in subjects with Type 2 diabetes. Diabetes Med. 2005;22:497–502
- . UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352:854–865
- . 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med. 2008;359:1577–1589
- . The incidence of congestive heart failure associated with antidiabetic therapies. Diabetes Metab Res Rev. 2005;21:51–57
- . Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group. N Engl J Med. 1995;333:541–549
- . Incidence of lactic acidosis in metformin users. Diabetes Care. 1999;22:925–927
- . Lactic acidosis in patients with diabetes treated with metformin. N Engl J Med. 1998;338:265–266
- . Biguanide related lactic acidosis: incidence and risk factors. Arch Med Res. 1992;23:19–24
- . Lactic acidosis rates in type 2 diabetes. Diabetes Care. 1998;21:1659–1663
- . Metformin. N Engl J Med. 1996;334:574–579
- . Safety issues on metformin use. Diabetes Care. 2003;26:3356–3357
- . Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database Syst Rev. 2006;(1):CD002967
- Insulin-sensitizing antihyperglycemic drugs and mortality after acute myocardial infarction: insights from the National Heart Care Project. Diabetes Care. 2005;28:1680–1689
- . Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study. Circulation. 2005;111:583–590
- . Improved clinical outcomes associated with metformin in patients with diabetes and heart failure. Diabetes Care. 2005;28:2345–2351
- Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review. BMJ. 2007;335:497
- . Cellular mechanism of action of metformin. Diabetes Care. 1990;13:696–704
- Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001;108:1167–1174
- . Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. Circulation. 2008;117:952–962
- Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes. 2002;51:2074–2081
- . Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. J Biol Chem. 2004;279:32771–32779
- AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest. 2004;114:495–503
- Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med. 2005;11:1096–1103
- . Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes. 2006;55:496–505
- Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients. Diabetes Care. 1996;19:934–939
- Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase. Circulation. 2009;119:2568–2577
- . Metformin therapy and outcomes in patients with advanced systolic heart failure and diabetes. J Card Fail. 2010;16:XXX-XXX
The authors have no conflicts to disclose.
PII: S1071-9164(09)01218-4
doi: 10.1016/j.cardfail.2009.12.007
© 2010 Elsevier Inc. All rights reserved.
« Previous
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Journal of Cardiac Failure
Volume 16, Issue 3
, Pages 207-210
, March 2010
