Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 171-181 , April 2009

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

  • Brian E. Jaski, MD, FACC

      Affiliations

    • San Diego Cardiac Center, San Diego, California
    • Corresponding Author InformationReprint requests: Dr. Brian E. Jaski, San Diego Cardiac Center, 3131 Berger Avenue, San Diego, CA92123. Phone: (858) 244-6800; Fax: (858) 244-6909.
    • ,
  • Mariell L. Jessup, MD

      Affiliations

    • Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • Donna M. Mancini, MD

      Affiliations

    • New York-Presbyterian Hospital/Columbia University Hospital, New York, New York
    • ,
  • Thomas P. Cappola, MD

      Affiliations

    • Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • Daniel F. Pauly, MD, PhD

      Affiliations

    • Shands Hospital at the University of Florida, Gainesville, Florida
    • ,
  • Barry Greenberg, MD

      Affiliations

    • University of California at San Diego Medical Center, San Diego, California
    • ,
  • Kenneth Borow, MD

      Affiliations

    • Wayne, Pennsylvania
    • ,
  • Howard Dittrich, MD

      Affiliations

    • University of California at San Diego, San Diego, California
    • ,
  • Krisztina M. Zsebo, PhD

      Affiliations

    • Celladon Corporation, La Jolla, California
    • ,
  • Roger J. Hajjar, MD

      Affiliations

    • Mount Sinai School of Medicine, New York, New York
    • ,
  • on Behalf of the Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) Trial Investigators.

Received 22 November 2008 ,Revised 26 January 2009 ,Accepted 26 January 2009.

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 Funding for this study was provided by Celladon Corporation, La Jolla, CA. RJH is supported in part by grants from the National Institutes of Health: R01 HL078691, HL080498, HL 78731, HL083156, and a Leducq Transatlantic Network.

 R.J. Hajjar: Celladon Corporation, ownership interest (includes stock and stock options, and rights in patents); D.M. Mancini, Celladon Corporation, consultant/advisory board; B. Greenberg, Celladon Corporation, consultant/advisory board; H. Dittrich, Celladon Corporation, ownership interest (includes stock options), consultant/advisory board; K. Borow, Celladon Corporation, significant, consultant/advisory board; K.M. Zsebo, Celladon Corporation, employment.

PII: S1071-9164(09)00035-9

doi: 10.1016/j.cardfail.2009.01.013

Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 171-181 , April 2009

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