Journal of Cardiac Failure
Volume 15, Issue 6 , Pages 523-528 , August 2009

Acute Left Ventricular Unloading in Dogs With Chronic Heart Failure: Continuous Aortic Flow Augmentation Versus Intra-Aortic Balloon Pumping

  • Hani N. Sabbah, PhD

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan
    • Corresponding Author InformationReprint requests: Hani N. Sabbah, PhD, FACC, Director of Cardiovascular Research, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, Michigan 48202. Tel.: (313) 916-7360; Fax: (313) 916-3001.
  • ,
  • Mengjun Wang, MD

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan
  • ,
  • Ramesh C. Gupta, PhD

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan
  • ,
  • Sharad Rastogi, MD

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan
  • ,
  • Itamar Ilsar, DVM

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan
  • ,
  • Tony Viole, MS

      Affiliations

    • Orqis Medical, Inc., Lake Forest, California
  • ,
  • Robert Brewer, MD

      Affiliations

    • Departments of Medicine and Surgery, Henry Ford Hospital, Detroit, Michigan

Received 30 April 2008 ,Revised 5 November 2008 ,Accepted 14 January 2009.

References 

  1. Krumholtz HM, Parent EM, Tu N, Vaccarino V, Wang Y, Radford MJ, et al. Readmission after hospitalization for congestive heart failure among Medicare beneficiaries. Arch Intern Med. 1997;157:99–104
  2. Nohria A, Lewis E, Stevenson LW. Medical management of advanced heart failure. JAMA. 2002;287:628–640
  3. Jain P, Massie BM, Gattis WA, Klein L, Gheorghiade M. Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization. Am Heart J. 2003;145:S3–17
  4. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, et al. for the HeartMate Investigators Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186–1195
  5. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, et al. for the Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435–1443
  6. Haithcock BE, Morita H, Fanous NH, Suzuki G, Sabbah HN. Hemodynamic unloading of the failing left ventricle using an arterial-to-arterial extracorporeal flow circuit. Ann Thorac Surg. 2004;77:158–163
  7. Konstam MA, Czerska B, Bohm M, Oren RM, Sadowski J, Khanal S, et al. Continuous aortic flow augmentation. A pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failure. Circulation. 2005;112:3107–3114
  8. Sabbah HN, Stein PD, Kono T, Gheorghiade M, Levine TB, Jafri S, et al. A canine model of chronic heart failure produced by multiple sequential coronary microembolizations. Am. J. Physiol. 1991;260:H1379–H1384
  9. Dodge HT, Sandler H, Baxley WA, Hawley RR. Usefulness and limitations of radiographic methods for determining left ventricular volume. Am J Cardiol. 1966;18:10–24
  10. Grossman W. Cardiac catheterization and angiography. 3rd ed.. Philadelphia: Lea & Febiger; 1986;
  11. Waage A, Brandtzaeg P, Halstensen A, Kierulf P, Espevik T. The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J Exp Med. 1989;169:333–338
  12. Hirano T, Akira S, Taga T, Kishimoto T. Biological and clinical aspects of interleukin 6. Immunol Today. 1990;11:443–449
  13. Bonow RO. New insights into the cardiac natriuretic peptides. Circulation. 1996;93:1946–1950
  14. Alvarez B, Radi R. Peroxynitrite reactivity with amino acids and proteins. Amino Acids. 2003;25:295–311
  15. Yagi K. Simple assay for the level of total lipid peroxides in serum and plasma. Methods Molec Biol. 1998;108:101–106
  16. Gharib M, Beizaie M. Correlation between negative near-wall shear stress in human aorta and various stages of congestive heart failure. Ann Biomed Eng. 2003;3:678–685
  17. Lu X, Kassab GS. Nitric oxide is significantly reduced in ex-vivo porcine arteries during reverse flow because of increased superoxide production. J Physiol. 2004;561:575–582

 Supported, in part, by a grant from Orqis Medical, Inc. and by a grant from the National Heart, Lung, and Blood Institute PO1 HL074237-05

 Dr. Sabbah has a research grant from and is a member of the Scientific Advisory Board of Orqis Medical, Inc; Tony Viole is a full-time employee of Orqis Medical, Inc.

PII: S1071-9164(09)00017-7

doi: 10.1016/j.cardfail.2009.01.003

Journal of Cardiac Failure
Volume 15, Issue 6 , Pages 523-528 , August 2009