Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 199-205 , April 2009

Unconventional End Points in Cardiovascular Clinical Trials: Should We Be Moving Away From Morbidity and Mortality?

  • Jay Cohn, MD, FACC

      Affiliations

    • University of Minnesota, Minneapolis, Minnesota
    • Corresponding Author InformationReprint requests: Jay Cohn, MD, FACC, Cardiovascular Division, MMC 508, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455. Tel: 612-625-5646.
  • ,
  • John G.F. Cleland, MD, FACC

      Affiliations

    • Department of Cardiology, University of Hull, Kingston-upon-Hull, United Kingdom
  • ,
  • Jacobus Lubsen, MD, PhD

      Affiliations

    • SOCAR Research, Switzerland and Erasmust Medical Centre, Rotterdam, the Netherlands
  • ,
  • Jeffrey S. Borer, MD, FACC

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
  • ,
  • Philippe Gabriel Steg, MD, FACC

      Affiliations

    • INSERM U-698, Paris, France
  • ,
  • Michael Perelman, MD

      Affiliations

    • Schering Plough, Kenilworth, New Jersey
  • ,
  • Faiez Zannad, MD

      Affiliations

    • Hypertension and Preventive Cardiology Division, Department of Cardiovascular Disease, Centre d'Investigations Cliniques INSERM-CHU, Nancy, France

Received 5 August 2008 ,Revised 22 October 2008 ,Accepted 23 October 2008.

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 Pfizer Inc. provided an unrestricted educational grant to CIC INSERM-CHU of Nancy, France, to support the workshop from which this manuscript was generated (coordinator: Faiez Zannad).

 Conflict of interest: None.

PII: S1071-9164(08)01053-1

doi: 10.1016/j.cardfail.2008.10.029

Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 199-205 , April 2009