Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 241-248 , April 2009

Statin Therapy and Clinical Outcomes in Heart Failure: A Propensity-Matched Analysis

  • Maral Ouzounian, MD

      Affiliations

    • Heart & Stroke/Richard Lewar Centre for Excellence, University of Toronto, and Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • ,
  • Jack V. Tu, MD, PhD

      Affiliations

    • Heart & Stroke/Richard Lewar Centre for Excellence, University of Toronto, and Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Divisions of General Internal Medicine and Cardiology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Peter C. Austin, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Departments of Public Health Sciences and Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    • ,
  • Alice Chong, BSc

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • ,
  • Peter P. Liu, MD

      Affiliations

    • Heart & Stroke/Richard Lewar Centre for Excellence, University of Toronto, and Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    • Canadian Institutes of Health Research, Ottawa, Ontario, Canada
    • ,
  • Douglas S. Lee, MD, PhD

      Affiliations

    • Heart & Stroke/Richard Lewar Centre for Excellence, University of Toronto, and Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests: Douglas S. Lee, MD, PhD, Institute for Clinical Evaluative Sciences, 2075 Bayview Ave Rm G-106, Toronto, Ontario, M4N 3M5 Canada.

Received 2 May 2008 ,Revised 9 October 2008 ,Accepted 21 October 2008.

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 The Institute for Clinical Evaluative Sciences is supported in part by a grant from the Ontario Ministry of Health and Long-Term Care. The opinions, results and conclusions are those of the authors and no endorsement by the Ministry of Health and Long-Term Care or by the Institute for Clinical Evaluative Sciences is intended or should be inferred. This study was supported by an operating grant from the Canadian Institutes of Health Research (CIHR) and a CIHR Team Grant in Cardiovascular Outcomes Research. M. Ouzounian is supported by a 2007 Research Fellowship Award from the Heart Failure Society of America and the Tailored Advanced Collaborative Training in Cadiovascular Sciences program of the CIHR; J. V. Tu is a Career Investigator of the Heart & Stroke Foundation of Ontario and Canada Research Chair in Health Services Research; P. P. Liu holds the Heart & Stroke/Polo Chair Professor of Medicine and Physiology at the University Health Network, University of Toronto and is Scientific Director, Institute of Circulatory and Respiratory Health, CIHR; P. C. Austin is supported by a New Investigator Award from the CIHR; D. S. Lee is a clinician-scientist of the CIHR.

 A preliminary version of the data in this manuscript was presented at the Scientific Sessions of the American Heart Association, November 5, 2007, in Orlando, Florida.

PII: S1071-9164(08)01050-6

doi: 10.1016/j.cardfail.2008.10.026

Journal of Cardiac Failure
Volume 15, Issue 3 , Pages 241-248 , April 2009

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