Journal of Cardiac Failure
Volume 14, Issue 4 , Pages 276-282 , May 2008

Investigating Pain in Heart Failure Patients: Rationale and Design of the Pain Assessment, Incidence & Nature in Heart Failure (PAIN-HF) Study

  • Sarah J. Goodlin, MD

      Affiliations

    • Patient-centered Education and Research, Salt Lake City, Utah
    • Corresponding Author InformationReprint requests: Sarah J. Goodlin, MD, Institute for Health Care Delivery Research, 36 South State Street, 21st Floor, Salt Lake City, UT 84111.
  • ,
  • Sue Wingate, RN, DNSC, CRNP

      Affiliations

    • Kaiser Permanente Mid Atlantic States, Silver Spring, Maryland
  • ,
  • Susan J. Pressler, DNS, RN

      Affiliations

    • University of Michigan School of Nursing, Ann Arbor, Michigan
  • ,
  • John R. Teerlink, MD

      Affiliations

    • School of Medicine, University of California, San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, California
  • ,
  • C. Porter Storey, MD

      Affiliations

    • Palliative Care, Colorado Permanente Medical Group, Denver, Colorado

Received 12 July 2007 ,Revised 16 January 2008 ,Accepted 17 January 2008.

References 

  1. Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics—2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113:e85–e151
  2. Goodlin SJ, Hauptman PJ, Arnold R, Grady K, Hershberger RE, Kutner J, et al. Consensus statement: palliative and supportive care in advanced heart failure. J Card Fail. 2004;10:200–209
  3. Grady KL, Jalowiec A, White-Williams C, Pifarre R, Kirklin JK, Bourge RC, et al. Predictors of quality of life in patients with advanced heart failure awaiting transplantation. J Heart Lung Transplant. 1995;14:2–10
  4. Walden JA, Stevenson LW, Dracup K, Hook JF, Moser DK, Hamilton M, et al. Extended comparison of quality of life between stable heart failure patients and heart transplant recipients. J Heart Lung Transplant. 1994;13:1109–1118
  5. Stanek EJ, Oates MB, McGhan WF, Denofrio D, Loh E. Preferences for treatment outcomes in patients with heart failure: symptoms versus survival. J Card Fail. 2000;6:225–232
  6. Kutner JS, Kassner CT, Nowels DE. Symptom burden at the end of life: hospice providers' perceptions. J Pain Symptom Manage. 2001;21:473–480
  7. Lynn J, Teno JM, Phillips RS, Wu AW, Desbiens N, Harrold J, et al. Perceptions by family members of the dying experience of older and seriously ill patients. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. Ann Intern Med. 1997;126:97–106
  8. Jaagosild P, Dawson NV, Thomas C, Wenger NS, Tsevat J, Knaus WA, et al. Outcomes of acute exacerbation of severe congestive heart failure: quality of life, resource use, and survival. SUPPORT Investigators. The Study to Understand Prognosis and Preferences for Outcomes and Risks of Treatments. Arch Intern Med. 1998;158:1081–1089
  9. Weiss SC, Emanuel LL, Fairclough DL, Emanuel EJ. Understanding the experience of pain in terminally ill patients. Lancet. 2001;357:1311–1315
  10. Walke LM, Gallo WT, Tinetti ME, Fried TR. The burden of symptoms among community-dwelling older persons with advanced chronic disease. Arch Intern Med. 2004;164:2321–2324
  11. Goodlin SJ, Kutner J, Connor S, Ryndes T, Houser J, Hauptman PJ. Hospice care for heart failure patients. J Pain Symptom Manage. 2005;29:525–528
  12. Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005;112:e154–e235
  13. American Pain Foundation. Available from: http://www.painfoundation.org/Voices/VoicesSurveyReport.pdfAccessed February 2008
  14. Turk DC. Clinical effectiveness and cost-effectiveness of treatments for patients with chronic pain. Clin J Pain. 2002;18:355–365
  15. Cleeland CS. The measurement of pain from metastatic bone disease: capturing the patient's experience. Clin Cancer Res. 2006;12:6236s–6242s
  16. Portenoy RK, Thaler HT, Kornblith AB, Lepore JM, Friedlander-Klar H, Kiyasu E, et al. The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. Eur J Cancer. 1994;30A:1326–1336
  17. Vogl D, Rosenfeld B, Breitbart W, Thaler H, Passik S, McDonald M, et al. Symptom prevalence, characteristics, and distress in AIDS outpatients. J Pain Symptom Manage. 1999;18:253–262
  18. Palliative Care - Heart Failure Education And Research Trials (PC-HEART) Collaborative. Available from: www.pc-heart.orgAccessedFebruary 4, 2008
  19. Di Bari M, Pozzi C, Cavallini MC, Innocenti F, Baldereschi G, De Alfieri W, et al. The diagnosis of heart failure in the community. Comparative validation of four sets of criteria in unselected older adults: the ICARe Dicomano Study. J Am Coll Cardiol. 2004;44:1601–1608
  20. Sueta CA, Bertoni AG, Massing MW, McArdle J, Duren-Winfield V, Davis J, et al. Managed care patients with heart failure: spectrum of ventricular dysfunction and predictors of medication utilization. J Card Fail. 2005;11:106–111
  21. Heiat A, Gross CP, Krumholz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. Arch Intern Med. 2002;162:1682–1688
  22. Zambroski CH, Moser DK, Lennie T, Chung ML, Heo S. Use of the memorial symptom assessment scale-heart failure in heart failure patients. Circulation. 2004;110:SIII-739
  23. Zambroski CH, Moser DK, Bhat G, Ziegler C. Impact of symptom prevalence and symptom burden on quality of life in patients with heart failure. Eur J Cardiovasc Nurs. 2005;4:198–206
  24. Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975;1:277–299
  25. Melzack R. The short-form McGill Pain Questionnaire. Pain. 1987;30:191–197
  26. McCreary C, Turner J, Dawson E. Principal dimensions of the pain experience and psychological disturbance in chronic low back pain patients. Pain. 1981;11:85–92
  27. Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994;23:129–138
  28. Williams VS, Smith MY, Fehnel SE. The validity and utility of the BPI interference measures for evaluating the impact of osteoarthritic pain. J Pain Symptom Manage. 2006;31:48–57
  29. Zelman DC, Gore M, Dukes E, Tai KS, Brandenburg N. Validation of a modified version of the brief pain inventory for painful diabetic peripheral neuropathy. J Pain Symptom Manage. 2005;29:401–410
  30. Tittle MB, McMillan SC, Hagan S. Validating the brief pain inventory for use with surgical patients with cancer. Oncol Nurs Forum. 2003;30:325–330
  31. Green CP, Porter CB, Bresnahan DR, Spertus JA. Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure. J Am Coll Cardiol. 2000;35:1245–1255
  32. Hauptman PJ, Masoudi FA, Weintraub WS, Pina I, Jones PG, Spertus JA. Cardiovascular Outcomes Research Consortium. Variability in the clinical status of patients with advanced heart failure. J Card Fail. 2004;10:397–402
  33. Lee DS, Austin PC, Rouleau JL, Liu PP, Naimark D, Tu JV. Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model. JAMA. 2003;290:2581–2587
  34. Gottlieb SS, Abraham W, Butler J, Forman DE, Loh E, Massie BM, et al. The prognostic importance of different definitions of worsening renal function in congestive heart failure. J Card Fail. 2002;8:136–141
  35. Koglin J, Pehlivanli S, Schwaiblmair M, Vogeser M, Cremer P, vonScheidt W. Role of brain natriuretic peptide in risk stratification of patients with congestive heart failure. J Am Coll Cardiol. 2001;38:1934–1941
  36. Lowe B, Spitzer RL, Grafe K, Kroenke K, Quenter A, Zipfel S, et al. Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians' diagnoses. J Affect Disord. 2004;78:131–140
  37. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–613
  38. Martin A, Rief W, Klaiberg A, Braehler E. Validity of the Brief Patient Health Questionnaire Mood Scale (PHQ-9) in the general population. Gen Hosp Psychiatry. 2006;28:71–77
  39. Borson S, Scanlan JM, Chen P, Ganguli M. The Mini-Cog as a screen for dementia: a population based sample. J Am Geriatr Soc. 2003;51:1451–1454
  40. Borson S, Scanlan J, Brush M, Vitaliano P, Dokmak A. The mini-cog: a cognitive “vital signs” measure for dementia screening in multi-lingual elderly. Int J Geriatr Psychiatry. 2000;15:1021–1027
  41. Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, et al. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA. 2003;289:3106–3116
  42. Vaglio J, Conard M, Poston WS, O'Keefe J, Haddock CK, House J, et al. Testing the performance of the ENRICHD Social Support Instrument in cardiac patients. Health Qual Life Outcomes. 2004;2:24
  43. Ahles TA, Martin JB. Cancer pain: a multidimensional perspective. Hosp J. 1992;8:25–48
  44. Goodlin SJ. Care of the older patient with pain. Curr Pain Headache Rep. 2004;8:277–280
  45. Weir MR. Renal effects of nonselective NSAIDs and coxibs. Cleve Clin J Med. 2002;69(Suppl 1):SI53–SI58
  46. Page J, Henry D. Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem. Arch Intern Med. 2000;160:777–784
  47. Heerdink E, Leufkens H, Herings R, Ottervanger J, Striker B, Bakker A. NSAIDs associated with increased risk of congestive heart failure in elderly patients taking diuretics. Arch Intern Med. 1998;158:1108–1112
  48. Mamdani M, Juurlink DN, Lee DS, Rochon PA, Kopp A, Naglie G, et al. Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: a population-based cohort study. Lancet. 2004;363:1751–1756
  49. Zuccala G, Pedone C, Cesari M, Onder G, Pahor M, Marzetti E, et al. The effects of cognitive impairment on mortality among hospitalized patients with heart failure. Am J Med. 2003;115:97–103
  50. Zuccala G, Marzetti E, Cesari M, Lo Monaco MR, Antonica L, Cocchi A, et al. Correlates of cognitive impairment among patients with heart failure: Results of a multicenter survey. Am J Med. 2005;118:496–502
  51. Pautex S, Herrmann F, Le Lous P, Fabjan M, Michel JP, Gold G. Feasibility and reliability of four pain self-assessment scales and correlation with an observational rating scale in hospitalized elderly demented patients. J Gerontol A Biol Sci Med Sci. 2005;60:524–529
  52. Sorkin LS, Xiao WH, Wagner R, Myers RR. Tumour necrosis factor-alpha induces ectopic activity in nociceptive primary afferent fibres. Neuroscience. 1997;81:255–262
  53. Empl M, Renaud S, Erne B, Fuhr P, Straube A, Schaeren-Wiemers N, et al. TNF-alpha expression in painful and nonpainful neuropathies. Neurology. 2001;56:1371–1377
  54. Christensen U, Schmidt L, Hougaard CO, Kriegbaum M, Holstein BE. Socioeconomic position and variations in coping strategies in musculoskeletal pain: a cross-sectional study of 1,287 40- and 50-year-old men and women. J Rehabil Med. 2006;38:316–321
  55. Conard MW, Heidenreich P, Rumsfeld JS, Weintraub WS, Spertus J. Cardiovascular Outcomes Research Consortium. Patient-reported economic burden and the health status of heart failure patients. J Card Fail. 2006;12:369–374

 All decisions regarding this manuscript were made by a guest editor.Funding for the PAIN-HF study was received from the Mayday Fund, New York, New York.

PII: S1071-9164(08)00026-2

doi: 10.1016/j.cardfail.2008.01.008

Journal of Cardiac Failure
Volume 14, Issue 4 , Pages 276-282 , May 2008