Journal of Cardiac Failure
Volume 13, Issue 8 , Pages 609-617, October 2007

The Effect of KW-3902, an Adenosine A1 Receptor Antagonist, on Renal Function and Renal Plasma Flow in Ambulatory Patients With Heart Failure and Renal Impairment

  • Howard C. Dittrich, MD

      Affiliations

    • NovaCardia, Inc, San Diego, California
    • Corresponding Author InformationReprint requests: Howard C. Dittrich, MD, NovaCardia, Inc., 12750 High Bluff Drive, Suite 300, San Diego, CA 92130.
  • ,
  • Dinesh K. Gupta, MD

      Affiliations

    • Cardiology Group PC, Tullahoma, Tennessee
  • ,
  • Terrence C. Hack, MD

      Affiliations

    • Primary Care Cardiology Research, Ayer, Massachusetts
  • ,
  • Thomas Dowling, PhD

      Affiliations

    • University of Maryland, Baltimore, Maryland
  • ,
  • Janice Callahan, PhD

      Affiliations

    • Callahan Associates Inc., San Diego, California
  • ,
  • Scott Thomson, MD

      Affiliations

    • Nephrology-Hypertension Division, University of California San Diego and Veterans Affairs San Diego Healthcare System, San Diego, California

Received 11 March 2007; received in revised form 15 August 2007; accepted 17 August 2007.

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 This study was sponsored by NovaCardia, Inc. (San Diego, California) and was conducted under an Investigational New Drug Application with the US Food and Drug Administration. All costs of this study were borne by NovaCardia, Inc.Howard Dittrich is an employee of NovaCardia, Inc., Dinesh Gupta and Terrence Hack received grants from NovaCardia, Inc. Thomas Dowling, Janice Callahan, and Scott Thomson received consulting fees from NovaCardia, Inc.Clinical Trial Registration information: (http://www.clinicaltrials.gov) NCT00159614.

PII: S1071-9164(07)01040-8

doi:10.1016/j.cardfail.2007.08.006

Journal of Cardiac Failure
Volume 13, Issue 8 , Pages 609-617, October 2007