Journal of Cardiac Failure
Volume 13, Issue 9 , Pages 765-768 , November 2007

Single-Photon Emission Computed Tomography After Nitrate Administration Predicts Cardiac Events in Patients With Previous Myocardial Infarction and Left Ventricular Dysfunction

  • Wanda Acampa, MD, PhD

      Affiliations

    • Departments of Biomorphological and Functional Sciences, Institute of Biostructures and Bioimages of the National Council of Research, Naples, Italy
    • ,
  • Laura Evangelista, MD

      Affiliations

    • SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
    • ,
  • Anna Rita Sorrentino, MD, PhD

      Affiliations

    • Departments of Biomorphological and Functional Sciences, Institute of Biostructures and Bioimages of the National Council of Research, Naples, Italy
    • ,
  • Mario Petretta, MD

      Affiliations

    • Department of Internal Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    • ,
  • Luca Luongo, MD

      Affiliations

    • Departments of Biomorphological and Functional Sciences, Institute of Biostructures and Bioimages of the National Council of Research, Naples, Italy
    • ,
  • Alberto Cuocolo, MD

      Affiliations

    • Departments of Biomorphological and Functional Sciences, Institute of Biostructures and Bioimages of the National Council of Research, Naples, Italy
    • Corresponding Author InformationReprint requests: Alberto Cuocolo, Department of Biomorphological and Functional Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.

Received 26 March 2007 ,Revised 22 May 2007 ,Accepted 24 May 2007.

References 

  1. Allman KC, Shaw LJ, Hachamovitch R, Udelson JE. Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis. J Am Coll Cardiol. 2002;39:1151–1158
  2. Udelson JE, Bonow RO, Dilsizian V. The historical and conceptual evolution of radionuclide assessment of myocardial viability. J Nucl Cardiol. 2004;11:318–334
  3. Eitzman D, al-Aouar Z, Kanter HL, vom Dahl J, Kirsh M, Deeb GM, et al. Clinical outcome of patients with advanced coronary artery disease after viability studies with positron emission tomography. J Am Coll Cardiol. 1992;20:559–565
  4. Sciagrà R, Pellegri M, Pupi A, Bolognese L, Bisi G, Carnovale V, et al. Prognostic implications of Tc-99m sestamibi viability imaging and subsequent therapeutic strategy in patients with chronic coronary artery disease and left ventricular dysfunction. J Am Coll Cardiol. 2000;36:739–745
  5. Bax JJ, Visser FC, Poldermans D, Elhendy A, Cornel JH, Boersma E, et al. Relationship between preoperative viability and postoperative improvement in LVEF and heart failure symptoms. J Nucl Med. 2001;42:79–86
  6. Sorrentino AR, Acampa W, Petretta M, Mainolfi C, Salvatore M, Cuocolo A. Comparison of the prognostic value of SPECT after nitrate administration and metabolic imaging by PET in patients with ischaemic left ventricular dysfunction. Eur J Nucl Med Mol Imaging. 2007;34:558–562
  7. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-dimensional Echocardiograms: recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echo. 1989;2:358–367
  8. Kaul S. Response of dysfunctional myocardium to dobutamine. The eyes see what the mind knows. J Am Coll Cardiol. 1996;27:1608–1611
  9. Cuocolo A, Acampa W, Nicolai E, Pace L, Petretta M, Salvatore M. Quantitative thallium-201 and technetium-99m sestamibi tomography at rest in detection of myocardial viability in patients with chronic ischemic left ventricular dysfunction. J Nucl Cardiol. 2000;7:8–15
  10. Acampa W, Cuocolo A, Petretta M, Bruno A, Castellani M, Finzi A, et al. Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: comparison with sestamibi and Tl-201 scintigraphy. J Nucl Cardiol. 2002;9:33–40
  11. Cox DR. Regression models and life table. J R Stat Soc B. 1972;34:187–220
  12. Harrell FE, Lee KL, Califf RM, Pryor DB, Rosati RA. Regression modelling strategies for improved prognostic prediction. Stats Med. 1984;3:143–152
  13. The Multicenter Postinfarction Research Group . Risk stratification and survival after myocardial infarction. N Engl J Med. 1983;309:331–336
  14. TIMI Study Group . Value of radionuclide rest and exercise left ventricular ejection fraction in assessing survival of patients after thrombolytic therapy for acute myocardial infarction: results of Thrombolysis In Myocardial Infarction (TIMI) phase II study. J Am Coll Cardiol. 1995;26:73–79
  15. Bax JJ, Poldermans D, Elhendy A, Boersma E, Raimtoola SH. Sensitivity, specificity, and predictive accuracies of various non-invasive techniques for detecting hibernating myocardium. Curr Probl Cardiol. 2001;26:141–186
  16. Chareonthaitawee P, Gersh BJ, Araoz PA, Gibbons RJ. Revascularization in severe left ventricular dysfunction: the role of viability testing. J Am Coll Cardiol. 2005;46:567–574
  17. Desideri A, Cortigiani L, Christen AI, Coscarelli S, Gregori D, Zanco P, et al. The extent of perfusion-F18-fluorodeoxyglucose positron emission tomography mismatch determines mortality in medically treated patients with chronic ischemic left ventricular dysfunction. J Am Coll Cardiol. 2005;46:1264–1269

PII: S1071-9164(07)00169-8

doi: 10.1016/j.cardfail.2007.05.007

Journal of Cardiac Failure
Volume 13, Issue 9 , Pages 765-768 , November 2007

Article Tools

* Image Usage & Resolution