Journal of Cardiac Failure
Volume 13, Issue 5 , Pages 331-339, June 2007

Isosorbide Dinitrate and Hydralazine in a Fixed-Dose Combination Produces Further Regression of Left Ventricular Remodeling in a Well-Treated Black Population With Heart Failure: Results From A-HeFT

  • Jay N. Cohn, MD

      Affiliations

    • From the Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota
    • Corresponding Author InformationReprint requests: Jay N. Cohn, MD, Professor of Medicine, Cardiovascular Division, MC 508, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455.
  • ,
  • S. William Tam, PhD

      Affiliations

    • NitroMed, Inc., Lexington, Massachusetts
  • ,
  • Inder S. Anand, MD

      Affiliations

    • From the Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota
  • ,
  • Anne L. Taylor, MD

      Affiliations

    • From the Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota
  • ,
  • Michael L. Sabolinski, MD

      Affiliations

    • NitroMed, Inc., Lexington, Massachusetts
  • ,
  • Manuel Worcel, MD

      Affiliations

    • NitroMed, Inc., Lexington, Massachusetts
  • ,
  • for the A-HeFT Investigators

Received 6 November 2006; received in revised form 1 March 2007; accepted 5 March 2007.

Minnesota, Minneapolis; Lexington, Massachusetts

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 All decisions regarding this manuscript were made by a guest editor.A-HeFT was supported by NitroMed. The fixed-dose combination of isosorbide dinitrate and hydralazine was provided as BiDil.All authors have received grant support from NitroMed, Inc (JNC, ISA, ALT), or are employees of NitroMed (MW, MLS, SWT). Dr. Cohn has a royalty relationship with NitroMed based on his patents of the drug combination.

PII: S1071-9164(07)00070-X

doi:10.1016/j.cardfail.2007.03.001

Journal of Cardiac Failure
Volume 13, Issue 5 , Pages 331-339, June 2007