Journal of Cardiac Failure
Volume 13, Issue 4 , Pages 259-262 , May 2007

VE/VCO2 Slope in Older Heart Failure Patients With Normal Versus Reduced Ejection Fraction Compared With Age-Matched Healthy Controls

  • Brian Moore, MS

      Affiliations

    • Section on Cardiology, Department of Internal Medicine
    • ,
  • Peter H. Brubaker, PhD

      Affiliations

    • Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina
    • ,
  • Kathryn P. Stewart, RDCS

      Affiliations

    • Section on Cardiology, Department of Internal Medicine
    • ,
  • Dalane W. Kitzman, MD

      Affiliations

    • Section on Cardiology, Department of Internal Medicine
    • Corresponding Author InformationReprint requests: Dalane W. Kitzman, MD, Professor, IM-Cardiology, Wake Forest University Health Sciences, Medical Center Blvd., Winston-Salem, NC 27157.

Received 19 December 2006 ,Accepted 27 December 2006.

References 

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  2. Kitzman DW, Gardin JM, Gottdiener JS, Arnold AM, Boineau R, Aurigemma GP, et al. Importance of heart failure with preserved systolic function in patients > or = 65 years of Age. Cardiovascular Health Study. Am J Cardiol. 2001;87:413–419
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  12. Rich MW. Epidemiology, pathophysiology, and etiology of congestive heart failure in older adults. J Am Geriatr Soc. 1997;45:968–974
  13. Bard RL, Gillespie BW, Clarke NS, Egan TG, Nicklas JM. Determining the best ventilatory efficiency measure to predict mortality in patients with heart failure. J Heart Lung Transplant. 2006;25:589–595
  14. Chua TP, Ponikowski P, Harrington D, Anker SD, Webb-Peploe K, Clark AL, et al. Clinical correlates and prognostic significance of the ventilatory response to exercise in chronic heart failure. J Am Coll Cardiol. 1997;29:1585–1590
  15. Metra M, Cas LD, Panina G, Visioli O. Exercise hyperventilation chronic congestive heart failure, and its relation to functional capacity and hemodynamics. Am J Cardiol. 1992;70:622–628
  16. Guazzi M, Myers J, Arena R. Cardiopulmonary exercise testing in the clinical and prognostic assessment of diastolic heart failure. J Am Coll Cardiol. 2005;46:1883–1890
  17. Witte KKA, Thackray SDR, Nikitin NP, Cleland JGF, Clark AL. Pattern of ventilation during exercise in chronic heart failure. Heart. 2003;89:610–614
  18. Gitt A, Wasserman K, Kilkowski C, Kleeman T, Kilkowski A, Bangert M, et al. Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death. Circulation. 2002;106:3079–3084

 Supported by N.I.H. Grants AG18915 and AG12257; The Claude D. Pepper Older Americans Independence Center of Wake Forest University N.I.H. Grant P60AG10484; The Research and Development Fund of The Center for Medical Ultrasound, and the General Clinical Research Center (grant #MO1RR07122) of the Wake Forest University School of Medicine of Wake Forest University.

PII: S1071-9164(06)01297-8

doi: 10.1016/j.cardfail.2006.12.005

Journal of Cardiac Failure
Volume 13, Issue 4 , Pages 259-262 , May 2007

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