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Journal of Cardiac Failure
Volume 12, Issue 7
, Pages 491-498
, September 2006
The Effect of Xanthine Oxidase Inhibition Upon Ejection Fraction in Heart Failure Patients: La Plata Study
References
- . Novel myofilament Ca2+-sensitizing property of xanthine oxidase inhibitors. Circ Res. 1998;83:423–430
- Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. Circ Res. 1999;85:437–445
- Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy. Circulation. 2001;104:2407–2411
- Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. Circ Res. 2002;90:297–304
- Enhanced expression and activity of xanthine oxidoreductase in the failing heart. J Mol Cell Cardiol. 2000;32:2083–2089
- . Allopurinol improves endothelial dysfunction in chronic heart failure. Circulation. 2002;106:221–226
- Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies. Circulation. 2002;105:2619–2624
- Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging. Circulation. 2003;107:1991–1997
- Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?. Circulation. 2004;110:2175–2179
- . Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy. Circ Res. 2004;95:1005–1011
- . Chronic xanthine oxidase inhibition prevents myofibrillar protein oxidation and preserves cardiac function in a transgenic mouse model of cardiomyopathy. Am J Physiol Heart Circ Physiol. 2005;289:H1512–H1518
- Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. SOLVD Investigators. JAMA. 1993;14:1702–1707
- . The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study. J Card Fail. 2005;11(6 Suppl):S149
- . Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31–41
- Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr. 1989;2:358–367
- . Recommendations regarding quantitation in M-mode echocardiographic measurements. Circulation. 1978;58:1072–1083
- . Echocardiographic determinations of left ventricular mass in man: anatomic validation of the method. Circulation. 1977;55:613–618
- . Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–310
- . The SAS system for mixed models, ed 3. Cary (NC): SAS Institute Inc; 1996;p. 87–134
- . Disproportionate enhancement of myocardial contractility by the xanthine oxidase inhibitor oxypurinol in failing rat myocardium. Cardiovasc Res. 2003;59:582–592
- . Phenotyping hypertrophy: eschew obfuscation. Circ Res. 2003;92:1171–1175
- . Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol. 2002;34:379–388
- . Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation. 2003;107:1053–1058
- . Mitochondrial oxidative stress in heart failure: “oxygen wastage” revisited. Circ Res. 2000;86:119–120
- Increased reactive oxygen species production and functional alterations in antioxidant enzymes in human failing myocardium. J Card Fail. 2005;11:473–480
- . Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study. 1971–1992: National Health and Nutrition Examination Survey. JAMA. 2000;283:2404–2410
- Allopurinol enhances the contractile response to dobutamine and exercise in dogs with pacing-induced heart failure. Circulation. 2001;103:750–755
- Xanthine oxidoreductase inhibition causes reverse remodeling in rats with dilated cardiomyopathy. Circ Res. 2006;98:271–279
- . RESOLVD Pilot Study Investigators. Reliability, validity, and responsiveness of the six-minute walk test in patients with heart failure. Am Heart J. 2001;142:698–703
- . Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure. Heart. 2005;91:749–753
- . Effect of nitric oxide on hemoprotein-catalyzed oxidative reactions. Nitric Oxide. 1998;2:37–44
- . Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. Am J Physiol. 1997;272:H2327–H2336
- . Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts. Cardiovasc Res. 1997;33:422–432
- . Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ Res. 2000;87:241–247
- . Role of troponin I proteolysis in the pathogenesis of stunned myocardium. Circ Res. 1997;80:393–399
- . Origin of contractile dysfunction in heart failure: calcium cycling versus myofilaments. Circulation. 1999;99:1077–1083
Drs Cingolani and Brown are employees of Cardiome Pharma Corporation, Vancouver, BC, Canada, which sponsored the clinical trial.
PII: S1071-9164(06)00255-7
doi: 10.1016/j.cardfail.2006.05.005
© 2006 Elsevier Inc. All rights reserved.
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Journal of Cardiac Failure
Volume 12, Issue 7
, Pages 491-498
, September 2006
